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淋巴细胞性漏斗神经垂体炎:临床概述

Lymphocytic infundibulo-neurohypophysitis: a clinical overview.

作者信息

Johnston Philip C, Chew Luen S, Hamrahian Amir H, Kennedy Laurence

机构信息

Department of Endocrinology, Diabetes and Metabolism, Cleveland Clinic Foundation, 9500 Euclid Avenue Desk F20, Cleveland, OH, 44195, USA.

Regional Center for Endocrinology and Diabetes, Royal Victoria Hospital, Belfast, Northern Ireland, UK.

出版信息

Endocrine. 2015 Dec;50(3):531-6. doi: 10.1007/s12020-015-0707-6. Epub 2015 Jul 29.

Abstract

Lymphocytic infundibulo-neurohypophysitis is an uncommon inflammatory disorder postulated to be autoimmune in origin. Because of the location of inflammation, it selectively affects the posterior lobe of the pituitary (neurohypophysis) and pituitary stalk (infundibulum). The most common presentation is central diabetes insipidus. Although the definitive diagnosis is established histologically by a pituitary biopsy, radiological imaging can be valuable in diagnosing this condition. In this paper, we provide an overview of the pathophysiology, investigations, management, and outcomes of lymphocytic infundibulo-neurohypophysitis.

摘要

淋巴细胞性漏斗神经垂体炎是一种罕见的炎症性疾病,推测其起源为自身免疫性。由于炎症的部位,它选择性地影响垂体后叶(神经垂体)和垂体柄(漏斗)。最常见的表现是中枢性尿崩症。虽然通过垂体活检在组织学上确立明确诊断,但放射影像学在诊断这种疾病时可能很有价值。在本文中,我们概述了淋巴细胞性漏斗神经垂体炎的病理生理学、检查、管理及预后情况。

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