Kakefuda Yuki, Sato Akira, Watabe Hiroaki, Aihara Hideaki, Nishina Hidetaka, Noguchi Yuichi, Hoshi Tomoya, Aonuma Kazutaka
Department of Cardiology, Tsukuba Medical Center Hospital, Tsukuba, Japan.
Division of Cardiovascular Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Heart Vessels. 2016 Jul;31(7):1196-9. doi: 10.1007/s00380-015-0720-y. Epub 2015 Jul 29.
Very late stent thrombosis (VLST) is a serious complication after percutaneous coronary intervention. However, the best therapy for VLST with late-acquired incomplete stent apposition and incomplete neointimal coverage remains unknown. In these cases, neointimal coverage was nearly complete and no late-acquired malapposition was detected at 18 months after Endeavor zotarolimus-eluting stent (ZES) implantation for the treatment of VLST with late-acquired incomplete stent apposition after sirolimus-eluting stent implantation. We presented that Endeavor ZES implantation may become an attractive therapeutic strategy for the treatment of VLST with late-acquired incomplete stent apposition and incomplete neointimal coverage.
极晚期支架血栓形成（VLST）是经皮冠状动脉介入治疗后的一种严重并发症。然而，对于伴有晚期获得性支架贴壁不全和新生内膜覆盖不全的VLST的最佳治疗方法仍不清楚。在这些病例中，西罗莫司洗脱支架植入后出现晚期获得性支架贴壁不全，采用安进佐他莫司洗脱支架（ZES）植入治疗VLST，18个月时新生内膜覆盖几乎完全，未检测到晚期获得性贴壁不良。我们提出，安进ZES植入可能成为治疗伴有晚期获得性支架贴壁不全和新生内膜覆盖不全的VLST的一种有吸引力的治疗策略。
