Nogi N
Nihon Hifuka Gakkai Zasshi. 1989 Nov;99(12):1243-54.
Allergy to dental metal alloys has been reported to occasionally cause dermatitis, stomatitis, lichen planus and pustulosis palmaris et plantaris. According to Faraday's law of electrolysis, when electric current flows into an anode, cationic metal ions dissolve in parallel with the amount of the electric current. Therefore, when patients hypersensitive to metals have suffered from the above mentioned persistent dermatoses, measurement of voltages and electric currents around the dental alloys of the patient's oral cavities was deemed necessary, in order to investigate whether or not such dental metals have been supplied causative metal ions to the patients. For the investigation of electrochemical dissolution of metal ions; firstly, voltages and electric currents between the mucous membrane and standard dental alloy tips placed in the oral cavities of each 15 healthy volunteers and patients were measured. Secondly, the same study was performed with the mucous membrane and actually installed dental metals with 158 patients who showed positive reactions to dental metal series patch test allergens composed of 19 reagents. The results were as follows: 1) Voltages between the mucous membranes and standard metal plates placed in the oral cavities varied depending on the composition of the dental metal. 2) The above-mentioned voltages changed when various food were present in the oral cavity. 3) With the dental metals actually present in the metal-hypersensitive patient's oral cavities, the voltages between the adjacent mucous membrane and dental metals varied greatly, depending on the individual patient rather than on the types of metal. Certain alloys acted as cathodes with some patients, but as anodes with others. 4) Amalgam and silver alloys showed higher voltages and more electric current with the smaller ranges of variation than other kinds of alloys. Both of these alloys tended to act as anodes, therefore, the electrochemical dissolution of metal ions was expected to be higher than with other metals. 5) The voltages and electric currents were often higher between mucous membrane and metals than between metals. These findings indicate that the patient's own mucous membrane acts as cathode for the electrochemical dissolution rather than the dental metals. 6) Measuring the voltage and electric current in the patient's oral cavities is technically easy, and is considered to be valuable since the tendancy of electrochemical dissolution of metal ions from the dental metals is clearly demonstrated.
据报道,对牙科金属合金过敏偶尔会引起皮炎、口腔炎、扁平苔藓和掌跖脓疱病。根据法拉第电解定律,当电流流入阳极时,阳离子金属离子会与电流的量并行溶解。因此,当对金属过敏的患者患有上述持续性皮肤病时,为了调查此类牙科金属是否向患者提供了致病金属离子,认为有必要测量患者口腔中牙科合金周围的电压和电流。为了研究金属离子的电化学溶解;首先,测量了15名健康志愿者和患者口腔中黏膜与标准牙科合金尖端之间的电压和电流。其次,对158名对由19种试剂组成的牙科金属系列斑贴试验过敏原呈阳性反应的患者,用黏膜和实际安装的牙科金属进行了同样的研究。结果如下:1)口腔中黏膜与标准金属板之间的电压因牙科金属的成分而异。2)当口腔中存在各种食物时,上述电压会发生变化。3)对于金属过敏患者口腔中实际存在的牙科金属,相邻黏膜与牙科金属之间的电压因个体患者而异,差异很大,而不是取决于金属类型。某些合金对一些患者起阴极作用,但对另一些患者起阳极作用。4)汞合金和银合金显示出更高的电压和更多的电流,变化范围比其他类型的合金小。这两种合金都倾向于起阳极作用,因此,预计金属离子的电化学溶解比其他金属更高。5)黏膜与金属之间的电压和电流通常高于金属之间的电压和电流。这些发现表明,患者自身的黏膜在电化学溶解中起阴极作用,而不是牙科金属。6)在患者口腔中测量电压和电流在技术上很容易,并且被认为是有价值的,因为清楚地证明了牙科金属中金属离子的电化学溶解趋势。