Malapit Christian A, Howell Amy R
Department of Chemistry, University of Connecticut , Storrs, Connecticut 06269-3060, United States.
J Org Chem. 2015 Sep 4;80(17):8489-95. doi: 10.1021/acs.joc.5b01255. Epub 2015 Aug 19.
Oxetanes are valuable intermediates in organic synthesis, and strategic manipulations of this strained heterocycle continue to emerge. In this Synopsis, recent, distinct approaches to construct heterocyclic systems using oxetanes are described. These include ring expansion, ring opening, and C-2 functionalization.