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[癌症遗传咨询与生活质量:检测前遗传咨询期间应对策略和心理病理症状的影响]

[Cancer genetic counseling and quality of life: the effect of coping strategies and psychopathological symptoms during pre-test genetic counseling].

作者信息

Di Mattei Valentina Elisabetta, Duchini Elena, Zucchi Paola, Patricelli Maria Grazia, Rognone Alessia, Di Pierro Rossella, Zambetti Milvia, Sarno Lucio

出版信息

Recenti Prog Med. 2015 Aug;106(8):380-4. doi: 10.1701/1960.21304.

Abstract

UNLABELLED

The cancer genetic counseling (CGC) identifies genetic mutations for hereditary neoplastic diseases, but little is known on its psychological effects on subjects.

METHODS

The present study involved women who underwent genetic counseling for breast or ovarian cancer: 19 unaffected, 43 current patients, and 28 past patients. The aim of the study was to examine the relation between coping strategies and the quality of life during genetic counseling before testing, considering the effects of psychopathological symptoms and the health status.

RESULTS

Results showed that the use of avoidance strategies led to a decrease in quality of life, and that this relationship was entirely mediated by the intensity of psychopathological symptoms, while the health status did not show any effect on it.

CONCLUSIONS

The study, which is the first in Italy, suggests the importance of assessing coping strategies in subjects who undergo the CGO to identify individuals who are at risk of decrease of psychological well-being. Indeed, psychological counselling improving coping strategies could preserve the psychological well-being of individuals.

摘要

未标注

癌症遗传咨询(CGC)可识别遗传性肿瘤疾病的基因突变,但对其对受检者心理影响的了解甚少。

方法

本研究纳入了接受乳腺癌或卵巢癌遗传咨询的女性:19名未患病者、43名现患患者和28名既往患者。本研究的目的是在检测前的遗传咨询期间,考虑心理病理症状和健康状况的影响,研究应对策略与生活质量之间的关系。

结果

结果显示,采用回避策略会导致生活质量下降,且这种关系完全由心理病理症状的强度介导,而健康状况对此没有任何影响。

结论

该研究是意大利的首例此类研究,表明在接受癌症遗传咨询的受检者中评估应对策略以识别心理健康可能下降风险个体的重要性。确实,改善应对策略的心理咨询可以维护个体的心理健康。

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