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[严重高甘油三酯血症诱发急性胰腺炎:一例病例报告及文献复习]

[Severe hypertriglyceridemia induced acute pancreatitis: a case report and review of the literature].

作者信息

Herrera Del Águila Dwight Denis, Garavito Rentería Jorge, Linarez Medina Karen, Lizarzaburu Rodríguez Víctor

机构信息

Universidad de San Martín de Porres. Lima, Perú.

Servicio de Gastroenterología y de la Unidad de Hígado, Hospital Nacional Arzobispo Loayza. Lima, Perú.

出版信息

Rev Gastroenterol Peru. 2015 Apr-Jun;35(2):159-64.

Abstract

Hypertriglyceridemia-induced acute pancreatitis occurs in about 1-4% of the cases. It is the third leading cause of pancreatitis after biliary and alcoholic etiology. Hypertriglyceridemia can be caused by primary causes, lipid metabolism disorders and secondary causes. A 32 year old man, born in Huancayo, with a history of diabetes mellitus type 2, severe mixed dyslipidemia with primary hypertriglyceridemia, was admitted to emergency with 10 days of abdominal pain with moderate intensity in epigastrium and left hypochondrium spreading to dorsal region after intake of high-fat meal. 24 hours before admission, pain exacerbates increasing intensity and causing nausea and bilious vomits. Therefore, all laboratory examinations are carried out resulting in hypertriglyceridemia-induced acute pancreatitis. For that reason, an adequate clinical history physical examination associated with laboratory and image examinations are important to consider hypertriglyceridemia as part of the etiology of acute pancreatitis.

摘要

高甘油三酯血症性急性胰腺炎约占所有病例的1%-4%。它是继胆源性和酒精性病因之后胰腺炎的第三大主要病因。高甘油三酯血症可由原发性病因、脂质代谢紊乱及继发性病因引起。一名32岁男性,出生于万卡约,有2型糖尿病病史,患有严重的混合性血脂异常伴原发性高甘油三酯血症,因在进食高脂餐后上腹部和左季肋部出现中度强度腹痛并蔓延至背部区域10天而急诊入院。入院前24小时,疼痛加剧,强度增加,并伴有恶心和胆汁性呕吐。因此,进行了所有实验室检查,结果诊断为高甘油三酯血症性急性胰腺炎。因此,结合实验室和影像学检查的充分临床病史及体格检查对于将高甘油三酯血症视为急性胰腺炎病因的一部分很重要。

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