[甲状旁腺腺瘤和甲状腺乳头状癌患者高钙血症诱发的胰腺炎]

[Hypercalcemia-induced pancreatitis in a patient with parathyroid adenoma and thyroid papillary carcinoma].

作者信息

Robles-Cuadros Juan Martín, Lastarria-Bamberger Carlos, Murillo-Pérez Diego, Rivas-Ceballos Jesús, Piscoya Alejandro

机构信息

Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas. Lima, Perú.

Hospital Emergencias Grau. Lima, Perú.

出版信息

Rev Gastroenterol Peru. 2015 Apr-Jun;35(2):179-81.

PMID:26228986

Abstract

Acute pancreatitis due to hypercalcemia secondary to primary hyperparathyroidism is a rare aetiology. We present a female patient with pancreatitis; with prior cholecystectomy, no alcohol usage or dyslipidemia. Laboratory studies showed, serum calcium 17.93 mg/dL and iPTH 441 pg/ml. Neck CT showed multinodular goiter and a parathyroid nodule. The patient underwent surgery after which serum Ca and PTH decreased. Biopsy showed follicular variant papillary thyroid carcinoma. This report discusses possible theories of association between parathyroid adenoma and hypercalcemic pancreatitis and describes the association with follicular variant papillary thyroid carcinoma, not previously described.

摘要

原发性甲状旁腺功能亢进继发高钙血症所致的急性胰腺炎是一种罕见的病因。我们报告一名患有胰腺炎的女性患者；既往有胆囊切除术史，无饮酒或血脂异常。实验室检查显示，血清钙为17.93mg/dL，iPTH为441pg/ml。颈部CT显示多结节性甲状腺肿和一个甲状旁腺结节。患者接受手术后血清钙和甲状旁腺激素水平下降。活检显示为滤泡型乳头状甲状腺癌。本报告讨论了甲状旁腺腺瘤与高钙血症性胰腺炎之间关联的可能理论，并描述了与滤泡型乳头状甲状腺癌的关联，此前未曾有过相关描述。