Arora Devender, Singh Ajeet, Sharma Vikrant, Bhaduria Harvendra Singh, Patel Ram Bahadur
Department of Biotechnology, G.B. Pant Engineering College, Pauri Garhwal, Uttarakhand, India.
Bioinformation. 2015 Jun 30;11(6):272-5. doi: 10.6026/97320630011272. eCollection 2015.
HgsDb, a database is developed to organize the data under a single platform to facilitate easy access for researcher to get information on migration and molecular risk assessment. In past, human beings migrate from one place to other over the globe in search of food and better habitat, where they got adapted. These adaptations are visible in the form of change in color, facial pattern, average height, eye shape, hair texture, etc. This leads to origin of different race of human being. The adaptations are remarkable when move from equator to either poles. There are hundreds of different haplogroups reported on both maternal and paternal sites. This database provides overview of seventy-six major Haplogroup of mt-DNA and Y-DNA with their sub classes supplemented with structural information of individual Haplogroup responsible for various factor such molecular risk assessment, migration and origin. They help genealogist to gain deep insight information about their maternal and paternal patterns. , we had collected data from open source such as National Center for Biotechnology (NCBI), to develop this database for providing information, which Will helps the medical biology, molecular biology, genealogy and for designing personalized medicine.
开发了一个名为HgsDb的数据库,用于在单一平台上整理数据,以便研究人员能够轻松获取有关迁移和分子风险评估的信息。过去,人类为了寻找食物和更好的栖息地在全球范围内从一个地方迁移到另一个地方,并在那里适应环境。这些适应表现为肤色、面部特征、平均身高、眼睛形状、头发质地等方面的变化。这导致了不同人类种族的起源。从赤道向两极迁移时,这种适应尤为显著。在母系和父系位点上报告了数百种不同的单倍群。该数据库提供了76个主要线粒体DNA和Y染色体DNA单倍群及其子类的概述,并补充了负责各种因素(如分子风险评估、迁移和起源)的各个单倍群的结构信息。它们帮助系谱学家深入了解其母系和父系模式。我们从美国国立生物技术信息中心(NCBI)等开源渠道收集数据,开发此数据库以提供信息,这将有助于医学生物学、分子生物学、系谱学以及设计个性化医疗。