Suppr超能文献

关于盆腔器官脱垂和尿失禁,次全腹式子宫切除术与全腹式子宫切除术的客观比较:一项长达14年随访的随机对照试验

Objective comparison of subtotal vs. total abdominal hysterectomy regarding pelvic organ prolapse and urinary incontinence: a randomized controlled trial with 14-year follow-up.

作者信息

Andersen Lea L, Alling Møller Lars M, Gimbel Helga M

机构信息

Department of Obstetrics and Gynecology, Nykøbing Falster Hospital, Nykøbing Falster, Denmark; Department of Women and Children's Health 7821, Juliane Marie Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; University of Southern Denmark, Denmark.

Department of Obstetrics and Gynecology, Roskilde Hospital, Roskilde, Denmark.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2015 Oct;193:40-5. doi: 10.1016/j.ejogrb.2015.06.033. Epub 2015 Jul 9.

Abstract

OBJECTIVE

To compare subtotal and total abdominal hysterectomy regarding objective assessment of pelvic organ prolapse, urinary incontinence and voiding function 14 years after hysterectomy for benign diseases.

STUDY DESIGN

Long-term follow-up of a randomized clinical trial of subtotal vs. total abdominal hysterectomy with objective outcomes. All randomized women still alive and living in Denmark (n=304) were invited to answer a questionnaire and come for clinical examination consisting of 20-min pad weighing test, urinary flow, measurement of residual urine, POP-Q measurement for pelvic organ prolapse, 3 day voiding diary and also filled out the pelvic floor distress inventory (PFDI-20) questionnaire.

RESULTS

We included 100/304 (32.9%) women (subtotal hysterectomy: 53, total hysterectomy: 47) in the clinical examinations. The study questionnaire was answered by 197 (64.8%) (subtotal: 97, total: 100), the PFDI-20 questionnaire was answered by 140 (46.1%) (subtotal: 68, total: 72). We found no difference between subtotal and total abdominal hysterectomy in the PFDI-20 scores or regarding objectively assessed urinary incontinence or pelvic organ prolapse. In the subtotal hysterectomy group, 31 (59.6%) women had objective stage 2 pelvic organ prolapse compared with 33 (70.2%) in the total hysterectomy group (P=0.27); however, only 6/31 and 9/33 had symptoms (P=0.45). There were more anterior pelvic organ prolapses in the total hysterectomy group (N=10) than in the subtotal hysterectomy group (N=4) (P=0.048). We found a higher mean maximum flow rate (Qmax) in the subtotal hysterectomy group (34.78ml/s) than in the total hysterectomy group (27.08ml/s) (P=0.042) as well as a higher mean functional capacity in the subtotal hysterectomy group (526ml) than in the total hysterectomy group (443ml) (P=0.0147) according to the voiding diary.

CONCLUSION

Subtotal and total abdominal hysterectomy are comparable regarding long-term objective pelvic organ prolapse and urinary incontinence. The subtotal hysterectomy group had a higher Qmax and voided volume.

摘要

目的

比较次全子宫切除术和全子宫切除术对良性疾病子宫切除术后14年盆腔器官脱垂、尿失禁及排尿功能的客观评估结果。

研究设计

一项关于次全子宫切除术与全子宫切除术的随机临床试验的长期随访,观察客观结果。邀请所有仍在世且居住在丹麦的随机分组女性(n = 304)回答问卷并前来接受临床检查,检查包括20分钟的卫生巾称重试验、尿流率、残余尿量测量、用于评估盆腔器官脱垂的盆腔器官脱垂量化分期(POP-Q)测量、3天排尿日记,同时填写盆底功能障碍量表(PFDI-20)问卷。

结果

我们纳入了100/304(32.9%)的女性进行临床检查(次全子宫切除术组:53例,全子宫切除术组:47例)。197例(64.8%)(次全子宫切除术组:97例,全子宫切除术组:100例)回答了研究问卷,140例(46.1%)(次全子宫切除术组:68例,全子宫切除术组:72例)回答了PFDI-20问卷。我们发现次全子宫切除术和全子宫切除术在PFDI-20评分、客观评估的尿失禁或盆腔器官脱垂方面没有差异。在次全子宫切除术组中,31例(59.6%)女性存在客观的盆腔器官脱垂2期,而全子宫切除术组为33例(70.2%)(P = 0.27);然而,只有6/31和9/33有症状(P = 0.45)。全子宫切除术组的前盆腔器官脱垂(N = 10)比次全子宫切除术组(N = 4)更多(P = 0.048)。根据排尿日记,我们发现次全子宫切除术组的平均最大尿流率(Qmax)(34.78ml/s)高于全子宫切除术组(27.08ml/s)(P = 0.042),次全子宫切除术组的平均功能容量(526ml)也高于全子宫切除术组(443ml)(P = 0.0147)。

结论

次全子宫切除术和全子宫切除术在长期客观的盆腔器官脱垂和尿失禁方面具有可比性。次全子宫切除术组的Qmax和排尿量更高。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验