Institute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No.600, Yishan Rd, Shanghai, China.
Department of Radiology, Shanghai East Hospital, Tong Ji University, School of Medicine, No.1800, Yuntai Rd, Shanghai, China.
J Cardiovasc Comput Tomogr. 2015 Nov-Dec;9(6):578-84. doi: 10.1016/j.jcct.2015.07.005. Epub 2015 Jul 23.
The J-CTO score is based on invasive angiography, combines several parameters of chronic total coronary occlusions (CTO), and is well established to predict the likelihood of success of percutaneous recanalization. The purpose of this study was to evaluate and validate a J-CTOCT score derived from coronary computed tomography angiography (coronary CTA).
Between April 2011 and December 2014, 159 consecutive patients were retrospectively included. All had at least one CTO in invasive angiography, had coronary CTA performed at an interval of no more than one week from invasive angiography, and had an attempt at percutaneous coronary intervention (PCI) following coronary CTA In parallel to the angiographic J-CTO score, the J-CTOCT score was determined by awarding one point each for a blunt vessel stump, bending > 45°, occlusion length ≥ 20 mm, presence of calcium covering > 50% of any vessel cross-section within the occlusion, or a previously failed attempt at PCI. a. Both scores were compared regarding their ability to predict successful recanalization.
A total of 171 CTO lesions were analyzed. Intraobserver (k = 0.814, p < 0.001) and interobserver agreement (k = 0.771, p < 0.001) for calculation of the J-CTOCT score were close. The mean occlusion length measured by coronary CTA was significantly shorter than in invasive angiography (27.6 ± 14.8 mm vs. 37.2 ± 18.8 mm, p < 0.001). The J-CTOCT score (mean: 1.9 ± 1.4) correlated closely to the angiographic J-CTO score (mean: 1.8 ± 1.3, r = 0.856, p < 0.001), and in 122/171 lesions (71%), the scores were identical. Both J-CTOCT score (area under curve: 0.882, p < 0.001) and angiographic J-CTO score (area under curve: 0.868, p < 0.001) yielded similarly high predictive value for successful guidewire crossing within 30 min (p = 0.496).
While the length of coronary occlusions in coronary CTA is significantly shorter than in invasive angiography, a J-CTOCT score determined by coronary CTA closely correlates to the angiographic J-CTO score. .
J-CTO 评分基于有创血管造影,结合了慢性完全闭塞(CTO)的多个参数,并且已经很好地确立了预测经皮再通成功的可能性。本研究的目的是评估和验证源自冠状动脉计算机断层扫描血管造影(冠状动脉 CTA)的 J-CTOCT 评分。
回顾性纳入 2011 年 4 月至 2014 年 12 月的 159 例连续患者。所有患者均在有创血管造影中至少有一条 CTO,且在有创血管造影后不超过一周内进行冠状动脉 CTA 检查,并在冠状动脉 CTA 后尝试经皮冠状动脉介入治疗(PCI)。与血管造影 J-CTO 评分平行,通过为钝性血管残端、弯曲度>45°、闭塞长度≥20mm、闭塞段内任何血管横截面积有>50%的钙覆盖、或先前尝试 PCI 失败各记 1 分,确定 J-CTOCT 评分。比较两种评分在预测成功再通方面的能力。
共分析了 171 条 CTO 病变。计算 J-CTOCT 评分的观察者内(k=0.814,p<0.001)和观察者间(k=0.771,p<0.001)一致性均接近。冠状动脉 CTA 测量的闭塞长度明显短于有创血管造影(27.6±14.8mm 与 37.2±18.8mm,p<0.001)。J-CTOCT 评分(平均值:1.9±1.4)与血管造影 J-CTO 评分(平均值:1.8±1.3,r=0.856,p<0.001)密切相关,在 171 条病变中有 122/171 条(71%)评分相同。J-CTOCT 评分(曲线下面积:0.882,p<0.001)和血管造影 J-CTO 评分(曲线下面积:0.868,p<0.001)在预测 30 分钟内导丝成功通过方面均具有较高的预测价值(p=0.496)。
虽然冠状动脉 CTA 中冠状动脉闭塞的长度明显短于有创血管造影,但由冠状动脉 CTA 确定的 J-CTOCT 评分与血管造影 J-CTO 评分密切相关。