Department of Cardiology, Higashi Takarazuka Satoh Hospital, Takarazuka, Japan.
Department of Cardiology, Higashi Takarazuka Satoh Hospital, Takarazuka, Japan.
JACC Cardiovasc Imaging. 2018 Feb;11(2 Pt 1):209-217. doi: 10.1016/j.jcmg.2017.01.028. Epub 2017 Jun 14.
The aim of this study was to compare the ability of conventional versus computed tomography angiography (CTA) to predict procedural success and 30-min wire crossing rates in percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions.
Coronary CTA can be used to assess the morphology of CTO lesions.
We examined 205 consecutive patients (218 CTO lesions) who underwent coronary CTA pre-PCI. The J-CTO (Multicenter CTO Registry of Japan) score (the sum of the following 5 binary parameters: blunt proximal cap, calcification, bending >45°, and length of occluded segment >20 mm plus previously failed PCI attempt) was calculated using both CTA and conventional coronary angiography and compared.
The median patient age was 69 years (interquartile range: 62 to 75 years), 82.4% were male, and a retrograde approach was attempted in 72 (33.0%) cases. The procedural success rate of the CTO-PCI procedures was 82.6%, and 29.4% of cases achieved 30-min wire crossing. The areas under the curve of the CTA-derived J-CTO score for predicting procedural success and 30-min wire crossing were significantly greater than those derived from conventional angiography (0.855 vs. 0.698; p < 0.001 for procedural success and 0.812 vs. 0.692; p < 0.001, for 30-min wire crossing). In addition, the areas under the curve of CTA-derived evaluations of calcification, bending, and occlusion length were significantly higher than those of derived from angiography for predicting procedural success.
The CTA-derived J-CTO score was a more useful predictor of both procedural success and 30-min wire crossing than the J-CTO score derived from conventional angiography.
本研究旨在比较常规血管造影与计算机断层血管造影(CTA)在预测慢性完全闭塞(CTO)病变经皮冠状动脉介入治疗(PCI)成功率和 30 分钟导丝通过率方面的能力。
冠状动脉 CTA 可用于评估 CTO 病变的形态。
我们检查了 205 例连续患者(218 例 CTO 病变),这些患者在 PCI 前进行了冠状动脉 CTA。使用 CTA 和常规冠状动脉造影计算 J-CTO(日本多中心 CTO 注册研究)评分(以下 5 个二进制参数的总和:钝性近端帽、钙化、弯曲>45°、闭塞节段长度>20mm 加上之前 PCI 失败尝试),并进行比较。
患者年龄中位数为 69 岁(四分位距:62 至 75 岁),82.4%为男性,72 例(33.0%)尝试逆行入路。CTO-PCI 手术的成功率为 82.6%,29.4%的病例在 30 分钟内实现了导丝通过。CTA 衍生的 J-CTO 评分预测手术成功率和 30 分钟导丝通过的曲线下面积明显大于传统血管造影衍生的评分(0.855 对 0.698;p<0.001 用于手术成功率和 0.812 对 0.692;p<0.001,用于 30 分钟导丝通过)。此外,CTA 衍生的钙化、弯曲和闭塞长度评估对预测手术成功率的曲线下面积明显高于血管造影衍生的评估。
与传统血管造影衍生的 J-CTO 评分相比,CTA 衍生的 J-CTO 评分在预测手术成功率和 30 分钟导丝通过率方面更为有用。