Rosen Ada, Taragano Lee, Condrea Alexander, Sidi Ami, Ron Yshai, Ginath Shimon
Isr Med Assoc J. 2015 Jun;17(6):351-5.
Fecal incontinence is defined as involuntary passage of stool through the anus. It may vary from soiling to complete evacuation. This involuntary loss of feces, flatus or urge incontinence adversely affects quality of life. Urinary urge incontinence is characterized by symptoms of frequency, urgency and urge incontinence (either alone or in combination). Urgency frequency syndrome is defined as symptoms of frequency and urgency without incontinence episodes.
To evaluate the efficacy of sacral neuromodulation on these pathologies.
Following a detailed investigation, 51 patients with either urinary or fecal incontinence, or both, who did not respond to medical and behavioral treatment were offered the temporary implant. Of the 51 patients 40 showed improvement and advanced for a permanent device.
After a mean follow-up of 5 years (range 1-8), there was a significant reduction in the number of incontinence episodes (P < 0.0001), and the number of pads used also declined significantly (P < 0.0001). A marked improvement in quality of life was reported by 71.4% of the women and 58.3% of the men.
Sacral neuromodulation as shown in this study appears to be a promising treatment for urinary and fecal incontinence and can dramatically improve patients' quality of life.
大便失禁定义为粪便不自主地经肛门排出。其程度可从粪便污染到完全排空不等。这种粪便、气体不自主排出或急迫性失禁会对生活质量产生不利影响。急迫性尿失禁的特征是尿频、尿急和急迫性失禁症状（单独出现或同时出现）。急迫性尿频综合征定义为仅有尿频和尿急症状而无失禁发作。
评估骶神经调节对这些病症的疗效。
经过详细检查，为51例对药物和行为治疗无反应的尿失禁或大便失禁患者，或两者皆有的患者提供了临时植入装置。51例患者中有40例病情改善并接受了永久性装置植入。
平均随访5年（范围1 - 8年）后，失禁发作次数显著减少（P < 0.0001），使用的尿垫数量也显著下降（P < 0.0001）。71.4%的女性和58.3%的男性报告生活质量有显著改善。
本研究显示，骶神经调节似乎是治疗尿失禁和大便失禁的一种有前景的方法，可显著改善患者的生活质量。
