Raedel Michael, Hartmann Andrea, Bohm Steffen, Walter Michael H
Department for Prosthetic Dentistry, Faculty of Medicine Carl Gustav Carus, Technische Universitaet, Dresden Fetscherstrasse 74, 01307 Dresden, Germany.
AGENON, Gesellschaft für Forschung und Entwicklung im Gesundheitswesen mbH, Kaunstrasse 21, 14163 Berlin, Germany.
J Dent. 2015 Oct;43(10):1218-22. doi: 10.1016/j.jdent.2015.07.016. Epub 2015 Jul 30.
The outcome of apicectomy in clinical reality is supposed to be different compared to outcomes reported from clinical trials. The objective of this study was to measure the outcome of apicectomies under practice conditions by mining an insurance data base.
This retrospective study was based on claims data of a major German national health insurance company (BARMER GEK). Through the company's data warehouse fee codes and treatment dates were accessible and allowed the tracing of clinical courses. Kaplan-Meier survival analyses for the target event 'extraction' were conducted for all teeth that underwent apicectomies within a 3 year period. Testing for differences among survival rates across groups was performed with the Log-Rank-test.
A total of 93,797 teeth in 77,636 patients could be traced after apicectomy. The cumulative 3-year survival rate was 81.6%. Anterior teeth showed a significantly higher survival rate of 84.0% compared to premolars (80.4%) and molars (80.2%). The survival rate in men (83.5%) was significantly higher than in women (80.6%). Analysis of survival by age revealed continuously declining survival rates with age (93.3% for subjects under 18 years of age to 75.6% for subjects over 84 years of age).
The 3-year outcomes of apicectomy were still acceptable for an intervention that is mostly conducted as a retreatment after failure of a preceding measure. However at a population level, the question remains to be answered whether other treatment options would potentially be more effective.
在临床实际中,根尖切除术的结果理应与临床试验报告的结果有所不同。本研究的目的是通过挖掘一个保险数据库来衡量实际操作条件下根尖切除术的结果。
这项回顾性研究基于德国一家大型国家健康保险公司(BARMER GEK)的理赔数据。通过该公司的数据仓库,可以获取费用代码和治疗日期,从而追踪临床病程。对在3年内接受根尖切除术的所有牙齿进行了针对目标事件“拔牙”的Kaplan-Meier生存分析。使用对数秩检验对各亚组的生存率差异进行检验。
根尖切除术后,共追踪到77636例患者的93797颗牙齿。3年累积生存率为81.6%。与前磨牙(80.4%)和磨牙(80.2%)相比,前牙的生存率显著更高,为84.0%。男性的生存率(83.5%)显著高于女性(80.6%)。按年龄进行的生存分析显示,生存率随年龄持续下降(18岁以下受试者为93.3%,84岁以上受试者为75.6%)。
对于一种大多作为先前治疗措施失败后的再次治疗而进行的干预措施而言,根尖切除术的3年结果仍可接受。然而,在总体人群层面,其他治疗选择是否可能更有效这一问题仍有待解答。