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1
Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis.
Mol Cell. 2015 Aug 20;59(4):677-84. doi: 10.1016/j.molcel.2015.06.029. Epub 2015 Jul 30.
2
Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage.
Mol Cell Biol. 2005 Jul;25(13):5380-8. doi: 10.1128/MCB.25.13.5380-5388.2005.
3
Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.
J Biol Chem. 2005 Oct 21;280(42):35081-4. doi: 10.1074/jbc.C500353200. Epub 2005 Aug 25.
4
The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP.
Nat Struct Mol Biol. 2007 Oct;14(10):912-20. doi: 10.1038/nsmb1306. Epub 2007 Sep 30.
5
p53 Protein is activated by Pin1: and also by Cu-SOD prion-like enzyme.
Med Hypotheses. 2005;65(1):32-4. doi: 10.1016/j.mehy.2005.01.041.
7
Interaction of p53 with prolyl isomerases: Healthy and unhealthy relationships.
Biochim Biophys Acta. 2015 Oct;1850(10):2048-60. doi: 10.1016/j.bbagen.2015.01.013. Epub 2015 Jan 29.
8
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults.
Nature. 2002 Oct 24;419(6909):853-7. doi: 10.1038/nature01120. Epub 2002 Oct 2.
9
Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage.
J Biol Chem. 2002 Dec 13;277(50):47976-9. doi: 10.1074/jbc.C200538200. Epub 2002 Oct 17.
10
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.
Nature. 2002 Oct 24;419(6909):849-53. doi: 10.1038/nature01116. Epub 2002 Oct 2.

引用本文的文献

2
Neurodegenerative diseases and neuroinflammation-induced apoptosis.
Open Life Sci. 2025 Feb 25;20(1):20221051. doi: 10.1515/biol-2022-1051. eCollection 2025.
3
Proline / Conformational Selection Controls 14-3-3 Binding.
J Am Chem Soc. 2025 Feb 19;147(7):5714-5724. doi: 10.1021/jacs.4c13462. Epub 2025 Feb 5.
4
Anisodamine (654-1/654-2) ameliorates septic kidney injury in rats by inhibiting inflammation and apoptosis.
Front Pharmacol. 2024 Sep 27;15:1421551. doi: 10.3389/fphar.2024.1421551. eCollection 2024.
5
DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma.
J Exp Clin Cancer Res. 2024 Jan 2;43(1):3. doi: 10.1186/s13046-023-02936-2.
6
Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression.
Biology (Basel). 2023 Dec 11;12(12):1511. doi: 10.3390/biology12121511.
7
Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis.
Nat Commun. 2023 Dec 16;14(1):8381. doi: 10.1038/s41467-023-44084-3.
8
Assignment of the disordered, proline-rich N-terminal domain of the tumour suppressor p53 protein using H and H-detected NMR measurements.
Biomol NMR Assign. 2023 Dec;17(2):309-314. doi: 10.1007/s12104-023-10160-4. Epub 2023 Oct 20.
9
Different types of cell death and their shift in shaping disease.
Cell Death Discov. 2023 Aug 4;9(1):284. doi: 10.1038/s41420-023-01581-0.
10
Proline Isomerization: From the Chemistry and Biology to Therapeutic Opportunities.
Biology (Basel). 2023 Jul 14;12(7):1008. doi: 10.3390/biology12071008.

本文引用的文献

1
Fluoroprolines as Tools for Protein Design and Engineering.
Angew Chem Int Ed Engl. 2001 Mar 2;40(5):923-925. doi: 10.1002/1521-3773(20010302)40:5<923::AID-ANIE923>3.0.CO;2-#.
2
Control of protein function by prolyl isomerization.
Biochim Biophys Acta. 2015 Oct;1850(10):1973-82. doi: 10.1016/j.bbagen.2014.12.019. Epub 2014 Dec 24.
3
Multidomain Peptidyl Prolyl cis/trans Isomerases.
Biochim Biophys Acta. 2015 Oct;1850(10):2005-16. doi: 10.1016/j.bbagen.2014.11.012. Epub 2014 Nov 18.
4
Lysine acetylation controls local protein conformation by influencing proline isomerization.
Mol Cell. 2014 Sep 4;55(5):733-44. doi: 10.1016/j.molcel.2014.07.004. Epub 2014 Aug 7.
5
The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat Struct Mol Biol. 2014 Jun;21(6):535-43. doi: 10.1038/nsmb.2829. Epub 2014 May 11.
6
Many players in BCL-2 family affairs.
Trends Biochem Sci. 2014 Mar;39(3):101-11. doi: 10.1016/j.tibs.2013.12.006. Epub 2014 Feb 3.
9
Examining BCL-2 family function with large unilamellar vesicles.
J Vis Exp. 2012 Oct 5(68):4291. doi: 10.3791/4291.
10
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53.
Cell Death Differ. 2013 Feb;20(2):198-208. doi: 10.1038/cdd.2012.112. Epub 2012 Aug 31.

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