Khaparde Kshitij, Jethani Pawan, Dewan Puneet K, Nair Sreenivas A, Deshpande Madhav Rao, Satyanarayana Srinath, Mannan Shamim, Moonan Patrick K
World Health Organization, Country Office for India, New Delhi 110011, India.
District TB Office, Rajnandgaon, Chhattisgarh 491441, India.
Tuberc Res Treat. 2015;2015:670167. doi: 10.1155/2015/670167. Epub 2015 Jul 6.
Rationale. Contact investigation is an established tool for early case detection of tuberculosis (TB). In India, contact investigation is not often conducted, despite national policy, and the yield of contact investigation is not well described. Objective. To determine the yield of evaluating household contacts of sputum smear-positive TB cases in Rajnandgaon district, Chhattisgarh, India. Methods. Among 14 public health care facilities with sputum smear microscopy services, home visits were conducted to identify household contacts of all registered sputum smear-positive TB cases. We used a standardized protocol to screen for clinical symptoms suggestive of active TB with additional referral for chest radiograph and sputa collection. Results. From December 2010 to May 2011, 1,556 household contacts of 312 sputum smear-positive TB cases were identified, of which 148 (9.5%) were symptomatic. Among these, 109 (73.6%) were evaluated by sputum examination resulting in 11 cases (10.1%) of sputum smear-positive TB and 4 cases (3.6%) of smear-negative TB. Household visits contributed additional 63% TB cases compared to passive case detection alone. Conclusion. A standard procedure for conducting household contact investigation identified additional TB cases in the community and offered an opportunity to initiate isoniazid chemoprophylaxis among children.
理论依据。接触者调查是结核病早期病例发现的既定工具。在印度,尽管有国家政策,但接触者调查并不经常开展,而且接触者调查的产出情况也没有得到很好的描述。目的。确定在印度恰蒂斯加尔邦赖金德冈地区对痰涂片阳性结核病病例的家庭接触者进行评估的产出情况。方法。在14个提供痰涂片显微镜检查服务的公共卫生保健机构中,进行家访以确定所有登记的痰涂片阳性结核病病例的家庭接触者。我们使用标准化方案筛查提示活动性结核病的临床症状,并额外转诊进行胸部X光检查和痰液采集。结果。2010年12月至2011年5月,共确定了312例痰涂片阳性结核病病例的1556名家庭接触者,其中148名(9.5%)有症状。在这些有症状的接触者中,109名(73.6%)接受了痰液检查,结果发现11例(10.1%)痰涂片阳性结核病病例和4例(3.6%)涂片阴性结核病病例。与仅通过被动病例发现相比,家访额外发现了63%的结核病病例。结论。开展家庭接触者调查的标准程序在社区中发现了额外的结核病病例,并为儿童启动异烟肼化学预防提供了机会。