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颅内狭窄的血管成形术和支架置入术

Angioplasty and Stenting for Intracranial Stenosis.

作者信息

Izumi Takashi, Imamura Hirotoshi, Sakai Nobuyuki, Miyachi Shigeru

出版信息

Neurol Med Chir (Tokyo). 2014;54 Suppl 2:46-53.

Abstract

Of the patients enrolled in the Japanese Registry of Neuroendovascular Therapy (JR-NET), a surveillance study in Japanese, 1133 patients who underwent intracranial percutaneous transluminal angioplasty (PTA)/stenting for intracranial stenosis during the period from 2005 to 2009 were investigated. A technical success was achieved in 98.3% of the patients, and 70.5% and 7.5% had a residual stenosis of <30% and ≥50%, respectively. The incidence of ischemic complications and hemorrhagic complications was as low as 7.7% and 2.5%, respectively, but tended to increase in patients who underwent stenting. While a significant correlation with ischemic complications was observed in previously untreated patients and patients who underwent stenting followed by post-dilatation, a significant correlation with hemorrhagic complications was observed in patients who received emergency treatment and those treated between 24 hours and 14 days of the onset. Flexible intracranial stents are expected to contribute to improvement in the treatment outcome.

摘要

在日本神经血管内治疗登记处(JR-NET)进行的一项日本监测研究中,对2005年至2009年期间接受颅内经皮腔内血管成形术(PTA)/颅内狭窄支架置入术的1133例患者进行了调查。98.3%的患者技术成功,残余狭窄<30%和≥50%的患者分别为70.5%和7.5%。缺血性并发症和出血性并发症的发生率分别低至7.7%和2.5%,但在接受支架置入术的患者中呈上升趋势。在未经治疗的患者以及接受支架置入术并随后进行后扩张的患者中,观察到与缺血性并发症有显著相关性;在接受急诊治疗的患者以及发病后24小时至14天之间接受治疗的患者中,观察到与出血性并发症有显著相关性。可弯曲颅内支架有望有助于改善治疗效果。

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