Department of Neurosurgery, Nagoya University Graduate School of Medicine.
Department of Neurosurgery, Kobe City Medical Center General Hospital.
Neurol Med Chir (Tokyo). 2020 May 15;60(5):256-263. doi: 10.2176/nmc.oa.2019-0271. Epub 2020 Apr 15.
A total of 907 patients enrolled in the Japanese Registry of Neuroendovascular Therapy (JR-NET)3, a surveillance study in Japan, who underwent intracranial percutaneous transluminal angioplasty (PTA)/stenting for intracranial stenosis during the period from 2010 to 2014 were investigated. Technical success was achieved in 97.5% of the patients, and 6.8% had a residual stenosis of ≥50%. The incidence rates of ischemic and hemorrhagic complications were as low as 5.3% and 3.1%, respectively, and the mortality rate was 1.9%. However, the mortality rate of cases with either complications was higher at 10.7%. About half of the treatment cases were performed between 24 h and 14 days after onset, and the incidence of perioperative complications was similar to that after at least 15 days. Although it is necessary to verify the effectiveness of PTA/stenting within 14 days, the results of this treatment were stable regardless of the intervention period.
共有 907 例患者入组日本神经血管介入治疗登记研究（JR-NET3），这是一项在日本开展的监测性研究，患者于 2010 年至 2014 年期间因颅内狭窄接受了颅内经皮腔内血管成形术（PTA）/支架置入术。97.5%的患者达到了技术上的成功，6.8%的患者残余狭窄程度≥50%。缺血性和出血性并发症的发生率分别低至 5.3%和 3.1%，死亡率为 1.9%。然而，有并发症的病例死亡率则高达 10.7%。约半数的治疗病例在发病后 24 小时至 14 天内进行，围手术期并发症的发生率与至少 15 天后相似。尽管有必要在 14 天内验证 PTA/支架置入术的有效性，但无论干预时间如何，该治疗的效果均稳定。
