[Lymphokine regulation of neutrophil phagocytic activity in patients with inflammatory diseases of the periodontium].

The authors have demonstrated the possibility of a purposeful correction of the immune system disorders in patients with periodontitis, one of such disorders being a lowered phagocytic activity of neutrophils. Lymphokines, immune system mediators, were used for in vitro regulation of neutrophilic phagocytosis. The effects of lymphokines obtained from the peripheral blood lymphocyte culture supernatants of normal subjects and periodontitis patients, and of the purified lymphokine M- and L-fractions normalizing the reduced neutrophilic phagocytosis in periodontitis were under study.