Horáková Martina, Ĺubušká Lucie, Kolář Milan, Hricová Kristýna, Vrba Radek, Neoral Čestmír, Zapletalová Jana
1 Surgical Intensive Care Unit, University Hospital Olomouc , Olomouc, Czech Republic .
2 Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University Olomouc , Olomouc, Czech Republic .
Surg Infect (Larchmt). 2015 Oct;16(5):513-7. doi: 10.1089/sur.2014.132. Epub 2015 Aug 3.
Presented are the findings from an analysis of respiratory inflammatory complications in patients undergoing esophageal replacement because of cancer. Respiratory complications are manifested most frequently within five post-operative days, thus, they are likely to be caused by potentially pathogenic micro-organisms originating from the primary or secondary microflora.
Sputum samples were collected 1-2 wks pre-operatively. In cases of positive microbiologic finding of some potential pathogens, individualized antibiotic prophylaxis was designed.
Patients with individualized prophylaxis had fewer respiratory complications (10%) than patients with general antibiotic prophylaxis (41%).
The approach to pre-operative sputum tests should be changed. If culture results are positive for bacteria with high resistance to antimicrobial agents or yeasts, the so-called individualized prophylaxis based on these particular results should be used.
