Huysmans H A, Vrakking M, van Boven W J
University Hospital Leiden, Dept. of Thoracic-Surgery, The Netherlands.
Z Kardiol. 1989;78 Suppl 7:43-5.
From more than 500 survivors of surgery for atrial septal defect of the secundum type (ASD II) operated upon between 1953 and 1965, 50 consecutive patients with an age of less than 6 years at the time of operation and 50 consecutive patients with an age of over 20 years at time of operation were chosen. Minimum follow-up in all cases was 20 years. In the younger age group there was a greater return to normal ECG and normal chest x-ray and patients had a normal exercise tolerance at late follow-up. When surgery was performed at an adult age fewer patients had normal ECGs and chest x-ray postoperatively, and overall there was a lower functional class postoperatively. There was, however, still a good longterm survival. Atrial arrhythmias developed in a considerable number of patients postoperatively and can develop even late after surgery in all age groups.
从1953年至1965年间接受继发孔型房间隔缺损（ASD II）手术的500多名幸存者中，选取了50例手术时年龄小于6岁的连续患者和50例手术时年龄大于20岁的连续患者。所有病例的最短随访时间为20年。在较年轻的年龄组中，心电图和胸部X线更易恢复正常，且患者在后期随访时运动耐量正常。在成年期进行手术时，术后心电图和胸部X线正常的患者较少，总体术后功能分级较低。然而，长期生存率仍然良好。相当数量的患者术后发生房性心律失常，且在所有年龄组中，甚至在术后很晚时仍可发生。
