晚期宫颈癌女性子宫动脉闭塞有效性降低的血管变化。
Vascular changes responsible for the reduced effectiveness of obliteration of uterine arteries in women with advanced cervical cancer.
作者信息
Raba Grzegorz, Szczupak Kamil, Stabiszewski Piotr, Skibinski Wojciech
机构信息
Institute of Obstetrics and Medical Lifesaving, University of Rzeszow, Rzeszow, Poland.
Hospital, Przemysl, Poland.
出版信息
Wideochir Inne Tech Maloinwazyjne. 2015 Jul;10(2):229-32. doi: 10.5114/wiitm.2015.52061. Epub 2015 Jun 8.
INTRODUCTION
Haemorrhages from the genital tract remain a major threat to the life of patients with advanced cervical cancer. It is possible to achieve haemostasis by both surgical techniques and the procedure of endovascular uterine artery embolization. However, in some women with loco-regionally advanced cervical cancer the obliteration of the uterine arteries is not effective.
AIM
Evaluation of morphological changes in uterine arteries in patients with advanced cervical cancer and comparison of their changes with the achieved haemostatic effect of obliteration.
MATERIAL AND METHODS
The prospective study included a group of 8 women with cervical cancer at a clinical stage of IIB to IIIC according to the FIGO classification. 3D quantitative coronary angiography (QCA) was performed before uterine embolization. The haemostatic effect of uterine artery embolization was compared with observed vascular changes.
RESULTS
Mean uterine artery length in patients who achieved complete hemostasis: 39.5 mm - right uterine artery; 38.7 mm - left uterine artery. Mean uterine artery length in patients who achieved partial satisfactory haemostasis: 32 mm - right uterine artery; 30.5 mm - left uterine artery. Mean uterine artery length in patients who achieved unsatisfactory haemostasis: 10.5 mm - right uterine artery; 19 mm - left uterine artery.
CONCLUSIONS
Shortening of uterine arteries worsens prognosis of the haemostatic effect of their obliteration in patients with advanced cervical cancer.
引言
生殖道出血仍然是晚期宫颈癌患者生命的主要威胁。通过手术技术和血管内子宫动脉栓塞术都有可能实现止血。然而，在一些局部区域晚期宫颈癌女性患者中，子宫动脉闭塞并不有效。
目的
评估晚期宫颈癌患者子宫动脉的形态学变化，并将其变化与实现的闭塞止血效果进行比较。
材料与方法
前瞻性研究纳入了一组根据国际妇产科联盟（FIGO）分类处于临床IIB至IIIC期的8例宫颈癌女性患者。在子宫栓塞术前进行三维定量冠状动脉造影（QCA）。将子宫动脉栓塞的止血效果与观察到的血管变化进行比较。
结果
实现完全止血的患者，右子宫动脉平均长度为39.5毫米；左子宫动脉平均长度为38.7毫米。实现部分满意止血的患者，右子宫动脉平均长度为32毫米；左子宫动脉平均长度为30.5毫米。实现不满意止血的患者，右子宫动脉平均长度为10.5毫米；左子宫动脉平均长度为19毫米。
结论
子宫动脉缩短会使晚期宫颈癌患者子宫动脉闭塞的止血效果预后变差。
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