Kwon Yong-Soon, Roh Hyun Jin, Ahn Jun Woo, Lee Sang-Hun, Im Kyong Shil
Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Ulsan University Hospital, Ulsan, Korea.
Department of Anesthesiology and Pain Medicine, Uijeongbu St Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul, Korea.
J Obstet Gynaecol Res. 2015 Jun;41(6):938-45. doi: 10.1111/jog.12649. Epub 2014 Dec 16.
This study aimed to determine the feasibility and safety of adenomyomectomy with transient occlusion of uterine arteries (TOUA) in patients with symptomatic diffuse uterine adenomyosis.
Twenty-six patients with symptomatic diffuse uterine adenomyosis underwent adenomyomectomy with TOUA by a single surgeon at Ulsan University Hospital between May 2011 and September 2012. Surgical outcomes included operative time, intraoperative injury to blood vessels, nerves, and pelvic organs and operative blood loss. We assessed the degree of improvement in dysmenorrhea and menorrhagia at the 4-month follow-up after completion of adjuvant gonadotrophin-releasing hormone agonist.
The mean age of patients was 37.73 years (range, 27-49 years). The mean total surgical time was 95.0 min (range, 60-145 min; SD, 34.49). The mean estimated blood loss was 191.54 mL (range, 80-400 mL; SD, 110.91) and there were no cases of injury to the uterine arteries or pelvic nerves. The mean time of TOUA was 9.79 min (range, 6-16 min; SD, 2.74). The mean duration of hospital stay was 5.65 days (range, 4-7 days; SD, 0.85). There were no major complications requiring reoperation or readministration during the mean follow-up period of 13.5 months. At the 7-month follow-up after adenomyomectomy with TOUA, complete remission of dysmenorrhea and menorrhagia was observed in 94.4% and 100% of patients, respectively.
Adenomyomectomy with TOUA could be a safe and effective surgical method in women with symptomatic diffuse uterine adenomyosis to preserve fertility.
本研究旨在确定对有症状的弥漫性子宫腺肌病患者行子宫腺肌瘤切除术联合子宫动脉短暂阻断术(TOUA)的可行性和安全性。
2011年5月至2012年9月期间,在蔚山大学医院,由一名外科医生对26例有症状的弥漫性子宫腺肌病患者实施了子宫腺肌瘤切除术联合TOUA。手术结果包括手术时间、术中血管、神经及盆腔器官损伤情况以及术中失血量。在辅助性促性腺激素释放激素激动剂治疗结束后的4个月随访时,我们评估了痛经和月经过多的改善程度。
患者的平均年龄为37.73岁(范围27 - 49岁)。平均总手术时间为95.0分钟(范围60 - 145分钟;标准差34.49)。平均估计失血量为191.54毫升(范围80 - 400毫升;标准差110.91),且无子宫动脉或盆腔神经损伤病例。TOUA的平均时间为9.79分钟(范围