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胆胰转流术/斯科皮纳罗手术在普拉德-威利综合征患者治疗中的效用。

The usefulness of biliopancreatic diversion/Scopinaro operation in treatment of patients with Prader-Willi syndrome.

作者信息

Michalik Maciej, Frask Agata, Lech Pawel, Zdrojewski Michal, Doboszynska Anna

机构信息

General and Minimally Invasive Surgery Department, University of Warmia and Mazury, Olsztyn, Poland.

General and Vascular Surgery Department, Ceynowa Hospital, Wejherowo, Poland.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2015 Jul;10(2):324-7. doi: 10.5114/wiitm.2015.49669. Epub 2015 Mar 10.

Abstract

Prader-Willi syndrome (PWS) is the most common form of obesity with a genetic basis. The short expected survival time due to numerous accompanying diseases and their complications is the reason for research on the maximally efficient method of treatment of obesity in this syndrome. Undertaken attempts of conservative treatment, for example with somatostatin, are ineffective. It seems that the only effective treatment of obesity in this syndrome may be surgical. In this article we present 2 cases of patients with PWS who underwent surgery consisting of biliopancreatic diversion (BPD)/Scopinaro procedure. The BPD/Scopinaro operation in selected cases of disciplined patients with a co-operative family, which we find of key importance, can be considered as one option of treatment of this syndrome in patients with prior neglect of conservative treatment.

摘要

普拉德-威利综合征(PWS)是最常见的具有遗传基础的肥胖症。由于众多伴随疾病及其并发症导致预期生存时间较短,这是研究该综合征中肥胖症最有效治疗方法的原因。采取的保守治疗尝试,例如使用生长抑素,是无效的。在该综合征中,肥胖症唯一有效的治疗方法似乎可能是手术。在本文中,我们介绍了2例接受了包括胆胰转流术(BPD)/斯科皮纳罗手术的普拉德-威利综合征患者。对于有合作家庭的自律患者的特定病例,我们认为这一点至关重要,BPD/斯科皮纳罗手术可被视为在先前忽视保守治疗的患者中治疗该综合征的一种选择。

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