Fabian June, Maher Heather Anne, Clark Chevon, Naicker Saraladevi, Becker Piet, Venter Willem Daniel Francois
Wits Donald Gordon Medical Centre, Parktown, Johannesburg, South Africa; Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
S Afr Med J. 2015 Jan 7;105(2):110-4. doi: 10.7196/samj.8369.
There are few published data from South Africa (SA) on the outcomes of black HIV-positive patients receiving chronic haemodialysis.
This retrospective study compared the incidences of vascular and infectious morbidity and mortality in black HIV-positive patients with those in a group of HIV-negative patients matched for ethnicity, age and gender. All the patients were receiving chronic haemodialysis in the medically insured healthcare sector of SA.
The incidence of tuberculosis and hospital admission rates for vascular access-related infections were significantly higher in the HIV-positive group than the HIV-negative group. The HIV-positive group had significantly lower albumin (p<0.05) and haemoglobin levels (p<0.01), but this did not impact on mortality. Survival in both groups was excellent. In the HIV-positive group, viral suppression rates were suboptimal with <50% of patients on antiretroviral therapy completely virally suppressed.
This study has shown that black HIV-positive patients receiving chronic haemodialysis in a healthcare-funded environment in SA have excellent overall survival in spite of higher hospital admission rates and higher infectious morbidity compared with HIV-negative patients.
关于南非（SA）接受慢性血液透析的黑人HIV阳性患者的治疗结果，已发表的数据很少。
这项回顾性研究比较了黑人HIV阳性患者与一组在种族、年龄和性别上匹配的HIV阴性患者的血管和感染性疾病发病率及死亡率。所有患者均在南非医疗保险医疗部门接受慢性血液透析。
HIV阳性组的结核病发病率和血管通路相关感染的住院率显著高于HIV阴性组。HIV阳性组的白蛋白（p<0.05）和血红蛋白水平（p<0.01）显著较低，但这并未影响死亡率。两组的生存率都很高。在HIV阳性组中，病毒抑制率不理想，接受抗逆转录病毒治疗的患者中不到50%的病毒被完全抑制。
这项研究表明，在南非由医疗基金资助的环境中接受慢性血液透析的黑人HIV阳性患者，尽管与HIV阴性患者相比住院率较高且感染性疾病发病率较高，但总体生存率很高。
