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Do cardiac aneurysms blow out?心脏动脉瘤会破裂吗?
Biophys J. 1979 Aug;27(2):301-16. doi: 10.1016/S0006-3495(79)85219-4.
2
Mechanics of left ventricular aneurysm.左心室动脉瘤的力学原理。
J Biomed Eng. 1986 Jan;8(1):9-23. doi: 10.1016/0141-5425(86)90025-7.
3
Ventricular aneurysms: a geometrical-dynamical model.
Jpn J Exp Med. 1989 Jun;59(3):89-102.
4
Characterization of dysfunctional remote myocardium in left ventricular anterior aneurysms and improvements following surgical ventricular restoration using cardiac magnetic resonance imaging: preliminary results.利用心脏磁共振成像对左心室前壁动脉瘤中功能失调的远隔心肌进行特征分析以及手术心室修复后的改善:初步结果
Interact Cardiovasc Thorac Surg. 2014 Sep;19(3):368-74. doi: 10.1093/icvts/ivu162. Epub 2014 Jun 6.
5
Ventricular aneurysm: pressure-volume relationships of a physical model.心室壁瘤:物理模型的压力-容积关系
Cardiology. 1981;67(4):193-205. doi: 10.1159/000173245.
6
[Bioengineering assessment of cardiac mechanical function: analysis of left ventricular wall stress and strain (author's transl)].心脏机械功能的生物工程评估:左心室壁应力与应变分析(作者译)
Iyodenshi To Seitai Kogaku. 1978 Dec;16(7):462-71.
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Spatial variations in wall thickness, material stiffness and initial shape affect wall stress and shape of intracranial aneurysms.
Neurol Res. 2007 Sep;29(6):569-77. doi: 10.1179/016164107X164193.
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[Significance of the transition zone for the contractility reserve of the residual ventricle in anterior wall aneurysms].[过渡区对前壁动脉瘤残余心室收缩储备的意义]
Verh Dtsch Ges Kreislaufforsch. 1977;43:306-7.
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[Left-ventricular hemodynamics in post-infarct aneurysms].[心肌梗死后室壁瘤的左心室血流动力学]
Kardiol Pol. 1980;23(8):639-48.
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Nonlinear anisotropic stress analysis of anatomically realistic cerebral aneurysms.解剖学逼真的脑动脉瘤的非线性各向异性应力分析
J Biomech Eng. 2007 Feb;129(1):88-96. doi: 10.1115/1.2401187.

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Mechanobiological stability: a new paradigm to understand the enlargement of aneurysms?机械生物学稳定性:理解动脉瘤扩大的新范式?
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本文引用的文献

1
Relation of sarcomere length and muscle length in resting myocardium.静息心肌中肌节长度与肌肉长度的关系。
Am J Physiol. 1970 May;218(5):1412-6. doi: 10.1152/ajplegacy.1970.218.5.1412.
2
Asymptotic slope of log pressure vs log volume as an approximate index of the diastolic elastic properties of the myocardium in man.对数压力与对数容积的渐近斜率作为人类心肌舒张弹性特性的近似指标。
Circulation. 1976 Mar;53(3):443-9. doi: 10.1161/01.cir.53.3.443.
3
Predicted effect of chronic apical aneurysms on the passive stiffness of the human left ventricle.慢性心尖部动脉瘤对人左心室被动僵硬度的预测影响。
Circ Res. 1978 Feb;42(2):255-63. doi: 10.1161/01.res.42.2.255.

心脏动脉瘤会破裂吗?

Do cardiac aneurysms blow out?

作者信息

Bogen D K, McMahon T A

出版信息

Biophys J. 1979 Aug;27(2):301-16. doi: 10.1016/S0006-3495(79)85219-4.

DOI:10.1016/S0006-3495(79)85219-4
PMID:262437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1328586/
Abstract

The possibility is suggested that cardiac aneurysms are formed when an infarcted region of the ventricular wall becomes elastically unstable and "blows out". The consequence of such a blowout could be a large saccular aneurysm or even cardiac rupture. We use a nonlinear stress-strain relation capable of describing both the passive and active myocardial wall to examine this possibility in terms of large-deformation membrane theory. Ventricular infarcts made of a material having physical properties like rubber would be expected to blow out, but those made of passive myocardium would not.

摘要

有一种可能性被提出,即当心室壁的梗死区域变得弹性不稳定并“膨出”时,心脏动脉瘤就会形成。这种膨出的后果可能是一个大的囊状动脉瘤,甚至是心脏破裂。我们使用一种能够描述被动和主动心肌壁的非线性应力-应变关系,根据大变形膜理论来研究这种可能性。由具有类似橡胶物理特性的材料制成的心室梗死区域预计会膨出,但由被动心肌制成的则不会。