伊朗棘阿米巴的现状：一篇叙述性综述文章。
Current Status of Acanthamoeba in Iran: A Narrative Review Article.
作者信息
Niyyati Maryam, Rezaeian Mostafa
机构信息
Dept. of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dept. of Medical Parasitology and Mycology, School of Public health, Tehran University of Medical Sciences, Tehran, Iran ; Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Iran J Parasitol. 2015 Apr-Jun;10(2):157-63.
BACKGROUND
Free-living amoebae belonging to the genus Acanthamoeba have an environmental distribution. Amoebic keratitis due to these protozoan parasites continue to rise in Iran and worldwide. In Iran, there are various researches regarding both morphological and molecular identification of Acanthamoeba spp. in environmental and clinical samples. However, there is no thorough review about Acanthamoeba genotypes and their distribution in environmental sources such as water, dust and biofilm in Iran. Besides, according to increasing cases of Amoebic keratitis in the region awareness regarding the pathogenic potential of these sight-threatening amoebae is of utmost importance.
METHODS
We conducted a thorough review based on the database sources such as MEDLINE, PubMed and Google scholar. No restrictions were placed on study date, study design or language of publication. We searched all valuable and relevant information considering the occurrence of the Acanthamoeba in both environmental and clinical samples.
RESULTS
According to our thorough review Acanthamoeba belonging to T4 genotype is the most prevalent type strain in environmental and clinical samples in several regions in Iran and worldwide, however, there are reports regarding Acanthamoeba belonging to other genotypes such as T2, T3, T5, T6 and T11 and the mentioned point could leads us to more researches with the goal of presenting the real genotype dominance of Acanthamoeba and related disease in the country.
CONCLUSION
Overall, the present review will focus on present status of genotypes of Acanthamoeba in Iran during recent years.
背景
棘阿米巴属的自由生活阿米巴在环境中广泛分布。由这些原生动物寄生虫引起的阿米巴性角膜炎在伊朗和全球范围内都呈上升趋势。在伊朗，针对环境和临床样本中棘阿米巴的形态学和分子鉴定有多项研究。然而，对于伊朗环境源（如水、灰尘和生物膜）中棘阿米巴基因型及其分布情况，尚无全面综述。此外，鉴于该地区阿米巴性角膜炎病例不断增加，了解这些威胁视力的阿米巴的致病潜力至关重要。
方法
我们基于MEDLINE、PubMed和谷歌学术等数据库来源进行了全面综述。对研究日期、研究设计或发表语言均无限制。我们搜索了所有与环境和临床样本中棘阿米巴出现情况相关的有价值信息。
结果
根据我们的全面综述，在伊朗的几个地区以及全球范围内，属于T4基因型的棘阿米巴是环境和临床样本中最常见的类型菌株，然而，也有关于属于其他基因型（如T2、T3、T5、T6和T11）的棘阿米巴的报道，这一点可能促使我们开展更多研究，以明确该国棘阿米巴的实际基因型优势及其相关疾病情况。
结论
总体而言，本综述将聚焦于近年来伊朗棘阿米巴基因型的现状。
Zotero 插件