从伊朗灰尘源中分离和鉴定潜在致病性棘阿米巴菌株。
Isolation and genotyping of potentially pathogenic Acanthamoeba strains from dust sources in Iran.
作者信息
Niyyati Maryam, Lorenzo-Morales Jacob, Rahimi Firoozeh, Motevalli-Haghi Afsaneh, Martín-Navarro Carmen M, Farnia Shohreh, Valladares Basilio, Rezaeian Mostafa
机构信息
Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Trans R Soc Trop Med Hyg. 2009 Apr;103(4):425-7. doi: 10.1016/j.trstmh.2008.12.007. Epub 2009 Jan 30.
Opportunistic free-living amoebae of the Acanthamoeba genus present genotypes/strains that are causative agents of Acanthamoeba keratitis (AK), with genotype T4 related to most AK cases worldwide. In order to prove that exposure to dirt and dust could be an important risk factor for contact lens wearers in Iran, 13 strains isolated from dust samples in this area were classified at the genotype level. Results revealed the presence of T4, T5 and T11 genotypes within these samples. To our knowledge, this is the first study presenting the identification of pathogenic genotypes of Acanthamoeba in dust samples in Iran and around the world.
棘阿米巴属的机会性自由生活阿米巴呈现出一些基因型/菌株，它们是棘阿米巴角膜炎（AK）的病原体，其中基因型T4与全球大多数AK病例相关。为了证明接触灰尘可能是伊朗隐形眼镜佩戴者的一个重要风险因素，对从该地区灰尘样本中分离出的13株菌株进行了基因型分类。结果显示这些样本中存在T4、T5和T11基因型。据我们所知，这是第一项在伊朗及全球范围内对灰尘样本中棘阿米巴致病基因型进行鉴定的研究。
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