中国人类和兔类中微小隐孢子虫的血清流行率。
Seroprevalence of Encephalitozoon cuniculi in Humans and Rabbits in China.
作者信息
Pan Yaoqian, Wang Shuai, Liu Xingyou, Li Ruizhen, Sun Yuqian, Gadahi Javaid Ali
机构信息
College of Animal Science and Henan Higher Education Engineering Technology Research Center for Animal Diseases Control and Residues Supervision, Henan Institute of Science and Technology, Xinxiang, Henan, PR China.
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, PR China.
出版信息
Iran J Parasitol. 2015 Apr-Jun;10(2):290-5.
BACKGROUND
Encephalitozoon cuniculi is a microsporidian parasite commonly found in rabbits that can infect humans, causing encephalitozoonosis. Our objective in this study was to evaluate the seroprevalence of this parasite in rabbits and humans in China.
METHODS
Overall, 300 serum samples each from clinically healthy rabbit and human were collected from three regions of China (Sichuan Province, Chongqing Municipality and Jilin Province) from January to September 2013 and tested for anti-E. Cuniculi antibodies using an ELISA.
RESULTS
An overall seroprevalence of E. cuniculi was recorded as 56/300 (18.76%) and 29/300 (9.76%) in rabbit and human sera, respectively. The seropositivity of rabbit samples collected from Jilin province was 41%, which was significantly higher (P<0.01) than Sichuan Province (9%) and Chongqing Municipality (6%). Three breeds of rabbit were used in the present study and antibody detection in Rex Rabbit was significantly (P<0.01) higher than Japanese White and New Zealand Rabbit. In human, Jilin province was more prevalent (18%) followed by Sichuan Province (6%) and Chongqing Municipality (5%).
CONCLUSIONS
The E. cuniculi was present and widespread among healthy rabbits and humans in China.
背景
兔脑炎微孢子虫是一种常见于兔子体内的微孢子虫寄生虫，可感染人类，引发兔脑炎微孢子虫病。本研究的目的是评估该寄生虫在中国兔子和人类中的血清阳性率。
方法
2013年1月至9月，从中国三个地区（四川省、重庆市和吉林省）采集了300份来自临床健康兔子和人类的血清样本，使用酶联免疫吸附测定法检测抗兔脑炎微孢子虫抗体。
结果
兔和人类血清中兔脑炎微孢子虫的总体血清阳性率分别为56/300（18.76%）和29/300（9.76%）。从吉林省采集的兔样本血清阳性率为41%，显著高于四川省（9%）和重庆市（6%）（P<0.01）。本研究使用了三个品种的兔子，其中獭兔的抗体检测阳性率显著高于日本白兔和新西兰兔（P<0.01）。在人类中，吉林省的感染率更高（18%），其次是四川省（6%）和重庆市（5%）。
结论
兔脑炎微孢子虫在中国健康兔子和人类中广泛存在。
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