Division of Comparative Pathology, Department of Pathology, Miller School of Medicine, University of Miami, P.O. Box 016960 R-46, Miami, FL, 33101, USA,
Parasitol Res. 2014 Jul;113(7):2757-9. doi: 10.1007/s00436-014-3930-9. Epub 2014 May 7.
Encephalitozoon cuniculi is an obligate intracellular microsporidian parasite that can result in clinical and subclinical infection in many species. In the present study, a serological survey was conducted using samples from 105 horses in the state of New Jersey; 49 of the samples were obtained from clinically abnormal animals. Five or 4.8% of 105 serum samples were found to demonstrate reactivity by ELISA with titers of 1:64 to 1:1,024. One of the samples was obtained from a clinically normal horse. Clinical signs and diagnoses from the other animals included lameness, colic, osteochondritis dissecans, and fever. All clinical issues were resolved with hospitalization and treatment without the institution of E. cuniculi-focused therapy. This is the first report on the detection of E. cuniculi antibodies in horses in the USA.
兔脑炎原虫是一种专性细胞内微孢子虫寄生虫，可导致许多物种出现临床和亚临床感染。在本研究中，对新泽西州的 105 匹马的样本进行了血清学调查；其中 49 个样本来自临床异常动物。通过 ELISA 检测发现，5 份（5.0%）或 105 份血清样本中的 1:64 至 1:1024 具有反应性。其中一份样本来自临床正常的马。其他动物的临床症状和诊断包括跛行、腹痛、骺软骨分离和发热。所有临床问题都通过住院和治疗得到解决，而无需针对兔脑炎原虫进行专门治疗。这是美国首次报告在马中检测到兔脑炎原虫抗体。
