Lawless M A, Troutman R C
Corneal and External Diseases, Royal North Shore Hospital, St Leonards, NSW, Australia.
Aust N Z J Ophthalmol. 1989 Nov;17(4):387-93. doi: 10.1111/j.1442-9071.1989.tb00559.x.
A series of 86 penetrating keratoplasties for keratoconus was analysed. The surgery, using an 8.2 mm donor cornea into an 8.0 mm recipient opening, was performed between January 1983 and January 1986. The donor cornea was secured by two opposing continuous sutures, placed at full corneal thickness under surgical keratometry control. Both sutures were removed on average 30 weeks after surgery. The mean postoperative sutures out astigmatism was 5.4 dioptres (range 0 to 19.0), and following astigmatism surgery in 17 eyes, the mean astigmatism was 4.3 dioptres (range 0 to 10.5). Graft reaction occurred in 11.6% but was cleared medically in all cases and no corneas were lost. One month after suture removal, with spectacle correction, 45.5% of the primary group achieved vision of 6/6, 90.7% were 6/9 or better, and 97.7% were 6/12 or better. Comparing these results with recently published data on epikeratoplasty, for the treatment of keratoconus, it is evident that penetrating keratoplasty offers the best means whereby the eye can obtain its full visual potential.
对86例圆锥角膜穿透性角膜移植术进行了分析。手术采用8.2mm供体角膜植入8.0mm受体植床开口,于1983年1月至1986年1月期间进行。供体角膜通过两条相对的连续缝线固定,在手术角膜曲率计控制下置于全角膜厚度处。两条缝线平均在术后30周拆除。术后缝线拆除时的平均散光为5.4屈光度(范围0至19.0),17只眼进行散光手术后,平均散光为4.3屈光度(范围0至10.5)。移植排斥反应发生率为11.6%,但所有病例均通过药物清除,无角膜丢失。缝线拆除1个月后,经眼镜矫正,原手术组45.5%的患者视力达到6/6,90.7%的患者视力为6/9或更好,97.7%的患者视力为6/12或更好。将这些结果与最近发表的关于角膜表面镜片术治疗圆锥角膜的数据进行比较,显然穿透性角膜移植术为眼睛发挥其全部视觉潜能提供了最佳方法。