Koa-Wing Michael, Nakagawa Hiroshi, Luther Vishal, Jamil-Copley Shahnaz, Linton Nick, Sandler Belinda, Qureshi Norman, Peters Nicholas S, Davies D Wyn, Francis Darrel P, Jackman Warren, Kanagaratnam Prapa
Imperial College Healthcare NHS Trust, Praed Street, London W2 1NY, United Kingdom.
Heart Rhythm Institute, University of Oklahoma Health Sciences Center, 1200 Everett Drive, Oklahoma City, USA.
Int J Cardiol. 2015 Nov 15;199:391-400. doi: 10.1016/j.ijcard.2015.07.017. Epub 2015 Jul 23.
Ripple Mapping (RM) is designed to overcome the limitations of existing isochronal 3D mapping systems by representing the intracardiac electrogram as a dynamic bar on a surface bipolar voltage map that changes in height according to the electrogram voltage-time relationship, relative to a fiduciary point.
We tested the hypothesis that standard approaches to atrial tachycardia CARTO™ activation maps were inadequate for RM creation and interpretation. From the results, we aimed to develop an algorithm to optimize RMs for future prospective testing on a clinical RM platform.
CARTO-XP™ activation maps from atrial tachycardia ablations were reviewed by two blinded assessors on an off-line RM workstation. Ripple Maps were graded according to a diagnostic confidence scale (Grade I - high confidence with clear pattern of activation through to Grade IV - non-diagnostic). The RM-based diagnoses were corroborated against the clinical diagnoses.
43 RMs from 14 patients were classified as Grade I (5 [11.5%]); Grade II (17 [39.5%]); Grade III (9 [21%]) and Grade IV (12 [28%]). Causes of low gradings/errors included the following: insufficient chamber point density; window-of-interest<100% of cycle length (CL); <95% tachycardia CL mapped; variability of CL and/or unstable fiducial reference marker; and suboptimal bar height and scar settings.
A data collection and map interpretation algorithm has been developed to optimize Ripple Maps in atrial tachycardias. This algorithm requires prospective testing on a real-time clinical platform.
涟漪映射(RM)旨在克服现有等时三维映射系统的局限性,通过在表面双极电压图上将心内电图表示为一个动态条带,该条带根据电图电压-时间关系相对于一个基准点在高度上发生变化。
我们检验了以下假设,即用于房性心动过速CARTO™激动标测的标准方法不足以创建和解释RM。根据结果,我们旨在开发一种算法,以优化RM,以便在临床RM平台上进行未来的前瞻性测试。
两名不知情的评估者在离线RM工作站上查看房性心动过速消融的CARTO-XP™激动标测图。根据诊断置信度量表对涟漪映射进行分级(I级 - 高度置信,有清晰的激动模式,直至IV级 - 无法诊断)。将基于RM的诊断与临床诊断进行对照核实。
来自14名患者的43个RM被分类为I级(5个[11.5%]);II级(17个[39.5%]);III级(9个[21%])和IV级(12个[28%])。低分级/错误的原因包括以下几点:腔室点密度不足;感兴趣窗口<心动周期长度(CL)的100%;映射的心动过速CL<95%;CL的变异性和/或不稳定的基准参考标记;以及条带高度和瘢痕设置不理想。
已开发出一种数据收集和标测解释算法,以优化房性心动过速中的涟漪映射。该算法需要在实时临床平台上进行前瞻性测试。