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胸膜孤立性纤维瘤:3例报告

Solitary fibrous tumor of the pleura: 3 case reports.

作者信息

Amorim Elias

机构信息

Urgency and Emergency Department, Hospital Universitário Presidente Dutra, Universidade Federal do Maranhão, São Luís, MA, Brazil.

出版信息

Rev Assoc Med Bras (1992). 2015 May-Jun;61(3):207-8. doi: 10.1590/1806-9282.61.03.207.

Abstract

INTRODUCTION

solitary fibrous tumor of the pleura (SFTP) is a rare tumor arising from mesenchymatous cells in submesothelial pleural tissue which, unlike mesothelioma, is not related to asbestos or smoking.

METHODS

report of four patients who underwent surgical treatment for giant SFTP and review of the pertinent literature.

RESULTS

of the four patients operated, two presented symptoms including cough, chest pain and feeling of compression, whereas the other two subjects were asymptomatic. All patients underwent complete surgical resection by wide posterolateral thoracotomy, and surgical specimens removed with minimum bleeding. None of the cases required complementary lobectomy or segmentectomy. All tumors were histologically benign.

CONCLUSION

complete resection of the lesion is the treatment of choice in all SFTP cases. Prognosis of the benign lesion is excellent, although close follow-up is necessary. In the rarer, more aggressive forms, treatment may be complemented by adjunctive chemotherapy or radiotherapy, the benefits of which have yet to be confirmed.

摘要

引言

胸膜孤立性纤维瘤(SFTP)是一种罕见的肿瘤,起源于间皮下胸膜组织中的间充质细胞,与间皮瘤不同,它与石棉或吸烟无关。

方法

报告4例接受手术治疗的巨大SFTP患者,并复习相关文献。

结果

4例接受手术的患者中,2例出现咳嗽、胸痛和压迫感等症状,而另外2例无症状。所有患者均通过广泛的后外侧开胸术进行了完整的手术切除,手术标本切除时出血最少。所有病例均无需进行辅助肺叶切除术或肺段切除术。所有肿瘤在组织学上均为良性。

结论

在所有SFTP病例中,完整切除病变是首选治疗方法。良性病变的预后良好,尽管需要密切随访。在较罕见、侵袭性更强的类型中,治疗可能辅以辅助化疗或放疗,但其益处尚未得到证实。

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