Kische Stephan, D'Ancona Giuseppe, Belu Ioan Christian, Stoeckicht Yannik, Agma Umut, Ortak Jasmin, Ince Hüseyin
Department of Cardiology and Cardiac Intervention, Vivantes Klinikum im Friedrichshain und Am Urban, Berlin, Germany Rostock University Medical Center, Rostock, Germany.
Department of Cardiology and Cardiac Intervention, Vivantes Klinikum im Friedrichshain und Am Urban, Berlin, Germany Rostock University Medical Center, Rostock, Germany
Eur J Cardiothorac Surg. 2015 Oct;48(4):e77-84. doi: 10.1093/ejcts/ezv267. Epub 2015 Aug 6.
To present results of endovascular treatment of complicated type B aortic dissection.
Patients with acutely complicated type B aortic dissection extending from the left sub-clavian artery to the abdominal aorta were treated. The strategy involved the placement of a covered endoprosthesis to seal the primary entry tear and, in cases where malperfusion persisted, distal extension with uncovered stents, to enhance true lumen (TL) expansion and reperfusion of the ischaemic arterial branches originating from the TL.
Thirty-five patients were included. Mean age was 63.1 (37-79) years and malperfusion syndrome occurred in 71.4%. Average aortic coverage with endoprostheses was 220.6 mm (136-355 mm). In 17 cases (48.5%), distal extension with uncovered stents was necessary. Thirty-day major morbidity was 28.5%, and mortality 2.8%. At follow-up (25.6 ± 19.5 months; 4-73 months), overall mortality was 15.2%, and aortic mortality 12.1%. Additional aortic intervention was necessary in 18.2%. Although patients undergoing distal extension with bare metal stents suffered most often from preoperative malperfusion, no significant differences were noted in the 30-day and follow-up clinical results. Follow-up angio-computed tomography showed complete thrombosis of the false lumen in the proximal half of the thoracic aorta in 76.4%. Patients treated with bare stents had significantly larger aortic TL sizes, at the different abdominal aorta levels.
In patients with complicated type B aortic dissection, tailored elongation with uncovered stents is a safe treatment of persistent malperfusion. Although the results presented are encouraging, randomized data and a longer follow-up are required to confirm benefits and complications of this strategy.
展示复杂B型主动脉夹层的血管内治疗结果。
对急性复杂B型主动脉夹层从左锁骨下动脉延伸至腹主动脉的患者进行治疗。治疗策略包括放置覆膜血管内支架以封闭原发破口,对于持续存在灌注不良的情况,使用裸支架进行远端延伸,以促进真腔扩张和源自真腔的缺血动脉分支的再灌注。
纳入35例患者。平均年龄为63.1岁(37 - 79岁),71.4%出现灌注不良综合征。血管内支架的平均主动脉覆盖长度为220.6 mm(136 - 355 mm)。17例(48.5%)需要使用裸支架进行远端延伸。30天主要发病率为28.5%,死亡率为2.8%。随访(25.6 ± 19.5个月;4 - 73个月)时,总死亡率为15.2%,主动脉相关死亡率为12.1%。18.2%需要再次进行主动脉干预。尽管接受裸金属支架远端延伸的患者术前灌注不良最为常见,但30天和随访临床结果未见显著差异。随访血管造影计算机断层扫描显示,76.4%的患者胸主动脉近端假腔完全血栓形成。在不同腹主动脉水平,接受裸支架治疗的患者主动脉真腔尺寸明显更大。
对于复杂B型主动脉夹层患者而言,使用裸支架进行个体化延伸是治疗持续灌注不良的安全方法。尽管所呈现的结果令人鼓舞,但仍需要随机数据和更长时间的随访来证实该策略的益处和并发症。