Jordan D R, Anderson R L, White G L, Mamalis N
Department of Ophthalmology, University of Ottawa.
Can J Ophthalmol. 1989 Dec;24(7):335-9.
Optic nerve gliomas are slow-growing tumours most commonly seen in children under 10 years of age. Rapidly progressive proptosis and rapid visual deterioration are uncommon but may occur owing to accumulation of mucoid material, necrosis or hemorrhage. We describe a patient with an optic nerve glioma who manifested sudden proptosis and blindness caused by hemorrhage within the optic nerve sheath. The visual acuity returned to 20/25 after surgical decompression of the nerve and high-dose steroid therapy. Histopathological examination was required to establish the diagnosis of optic nerve glioma with extensive calcification. Optic nerve decompression or short-term high-dose steroid therapy, or both, may be helpful in recovering visual function in selected patients with optic nerve gliomas who have acute visual loss.
视神经胶质瘤是生长缓慢的肿瘤，最常见于10岁以下儿童。快速进展性眼球突出和快速视力恶化并不常见，但可能由于黏液样物质积聚、坏死或出血而发生。我们描述了一名患有视神经胶质瘤的患者，其因视神经鞘内出血而出现突然的眼球突出和失明。在对视神经进行手术减压和大剂量类固醇治疗后，视力恢复到了20/25。需要进行组织病理学检查以确诊伴有广泛钙化的视神经胶质瘤。视神经减压或短期大剂量类固醇治疗，或两者兼用，可能有助于某些因急性视力丧失而患有视神经胶质瘤的患者恢复视觉功能。
