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[急性痛风性关节炎与类风湿关节炎鉴别诊断中的血液免疫学检查]

[Immunologic examination of the blood in the differential diagnosis of acute gouty arthritis and rheumatoid arthritis].

作者信息

Hrncír Z, Ettlerová E, Bradna P, Tichý M, Zaydlar K

出版信息

Cas Lek Cesk. 1989 Dec 1;128(49):1560-2.

PMID:2624928
Abstract

In 16 patients with acute gouty arthritis, 30 IgM RF seropositive cases of rheumatoid arthritis (RA) and 20 IgM RF seronegative cases of RA the values of 14 indicators of antibody and natural immunity were assessed in serum. The assembled data were evaluated by step-wise discrimination analysis. This made it possible to select consecutively signs important for the differentiation of acute gouty arthritis from IgM RF seropositive RA (immunocomplexes, beta-2 microglobulin, C3) and for its differentiation from IgM RF seronegative RA (IgE, C3, transferrin, free SH groups). Thus obtained classification functions make it possible to classify correctly, random subjects with a probability of 76.7-93.7%.

摘要

对16例急性痛风性关节炎患者、30例IgM类风湿因子(RF)血清阳性的类风湿关节炎(RA)患者以及20例IgM RF血清阴性的RA患者的血清中14项抗体和自然免疫指标的值进行了评估。对汇总数据进行逐步判别分析。这使得能够依次选择对于区分急性痛风性关节炎与IgM RF血清阳性RA(免疫复合物、β2微球蛋白、C3)以及区分急性痛风性关节炎与IgM RF血清阴性RA(IgE、C3、转铁蛋白、游离巯基)重要的指标。由此获得的分类函数能够以76.7% - 93.7%的概率正确分类随机受试者。

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