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符合经皮消融标准的患者接受部分肾切除术的结果。

Outcomes of partial nephrectomy in patients who meet percutaneous ablation criteria.

作者信息

Harris Kelly T, Ball Mark W, Gorin Michael A, Allaf Mohamad E, Pierorazio Phillip M

机构信息

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

Cent European J Urol. 2015;68(2):132-6. doi: 10.5173/ceju.2015.528. Epub 2015 Feb 27.

Abstract

INTRODUCTION

Treatment options for small renal masses include partial nephrectomy (PN), ablation and active surveillance. We sought to compare patients who met the criteria for percutaneous ablation but underwent robotic PN to the rest of our robotic PN cohort. This was done in order to detect any safety concerns and to define any risk factors that might contraindicate the use of robotic PN, an oncologically superior procedure, in patients who qualify for ablation.

MATERIAL AND METHODS

Our departmental renal mass registry was queried for patients who underwent robotic PN but also met criteria for percutaneous ablation. These were compared to the rest of the robotic PN cohort. Demographics, perioperative characteristics and recurrence data were compared.

RESULTS

Overall, 321 robotic PNs were identified. Of these, 26 (8.1%) met ablation criteria. Among patient characteristics, age and BMI were similar in both groups. Among operative characteristics, estimated blood loss (EBL) and operative time were similar. Warm ischemia time was significantly less for patients who met ablation criteria (14 vs. 17 minutes, p = 0.002). Mean tumor size was smaller for patients who met ablation criteria (2.3 vs. 2.7 cm, p = 0.012). Among postoperative characteristics, complications were similar overall and when present, stratified by Clavien grade.

CONCLUSIONS

Robotic PN is a safe, effective treatment option for small renal masses, even in patients who meet ablation criteria. There were no recurrences in our cohort and the majority of complications were Clavien grade 1.

摘要

引言

小肾肿瘤的治疗选择包括部分肾切除术(PN)、消融术和主动监测。我们试图将符合经皮消融标准但接受机器人辅助PN的患者与我们机器人辅助PN队列中的其他患者进行比较。这样做是为了发现任何安全问题,并确定可能使机器人辅助PN(一种在肿瘤学上更优的手术)在符合消融标准的患者中使用受限的任何风险因素。

材料与方法

我们查询了科室的肾肿瘤登记处,以找出接受机器人辅助PN但也符合经皮消融标准的患者。将这些患者与机器人辅助PN队列中的其他患者进行比较。比较了人口统计学、围手术期特征和复发数据。

结果

总体而言,共识别出321例机器人辅助PN手术。其中,26例(8.1%)符合消融标准。在患者特征方面,两组的年龄和体重指数相似。在手术特征方面,估计失血量(EBL)和手术时间相似。符合消融标准的患者热缺血时间明显更短(14分钟对17分钟,p = 0.002)。符合消融标准的患者平均肿瘤大小更小(2.3厘米对2.7厘米,p = 0.012)。在术后特征方面,总体并发症相似,且出现并发症时,按Clavien分级分层。

结论

机器人辅助PN是小肾肿瘤的一种安全、有效的治疗选择,即使是在符合消融标准的患者中。我们的队列中没有复发情况,且大多数并发症为Clavien I级。

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