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使用人造橡胶肌肉的心脏支持装置:主动动态心肌成形术的初步研究

Cardiac supporting device using artificial rubber muscle: preliminary study to active dynamic cardiomyoplasty.

作者信息

Saito Yoshiaki, Suzuki Yasuyuki, Goto Takeshi, Daitoku Kazuyuki, Minakawa Masahito, Fukuda Ikuo

机构信息

Department of Thoracic and Cardiovascular Surgery, Hirosaki University School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.

Department of Clinical Engineering, Hirosaki University School of Medicine and Hospital, Aomori, Japan.

出版信息

J Artif Organs. 2015 Dec;18(4):377-81. doi: 10.1007/s10047-015-0860-y. Epub 2015 Aug 8.

DOI:10.1007/s10047-015-0860-y
PMID:26253252
Abstract

Dynamic cardiomyoplasty is a surgical treatment that utilizes the patient's skeletal muscle to support circulation. To overcome the limitations of autologous skeletal muscles in dynamic cardiomyoplasty, we studied the use of a wrapped-type cardiac supporting device using pneumatic muscles. Four straight rubber muscles (Fluidic Muscle, FESTO, Esslingen, Germany) were used and connected to pressure sensors, solenoid valves, a controller and an air compressor. The driving force was compressed air. A proportional-integral-derivative system was employed to control the device movement. An overflow-type mock circulation system was used to analyze the power and the controllability of this new device. The device worked powerfully with pumped flow against afterload of 88 mmHg, and the beating rate and contraction/dilatation time were properly controlled using simple software. Maximum pressure inside the ventricle and maximum output were 187 mmHg and 546.5 ml/min, respectively, in the setting of 50 beats per minute, a contraction/dilatation ratio of 1:2, a preload of 18 mmHg, and an afterload of 88 mmHg. By changing proportional gain, contraction speed could be modulated. This study showed the efficacy and feasibility of a pneumatic muscle for use in a cardiac supporting device.

摘要

动力性心肌成形术是一种利用患者骨骼肌来支持循环的外科治疗方法。为了克服动力性心肌成形术中自体骨骼肌的局限性,我们研究了使用一种包裹式心脏支持装置,该装置采用气动肌肉。使用了四条直橡胶肌肉(流体肌肉,费斯托公司,德国埃斯林根),并将其连接到压力传感器、电磁阀、控制器和空气压缩机上。驱动力为压缩空气。采用比例积分微分系统来控制装置的运动。使用溢流型模拟循环系统来分析这种新装置的功率和可控性。该装置在对抗88 mmHg后负荷的情况下能有力地工作并产生泵血流量,且通过简单软件可适当控制心率和收缩/舒张时间。在每分钟50次心跳、收缩/舒张比为1:2、前负荷为18 mmHg和后负荷为88 mmHg的设定条件下,心室内的最大压力和最大输出量分别为187 mmHg和546.5 ml/min。通过改变比例增益,可以调节收缩速度。本研究表明了气动肌肉用于心脏支持装置的有效性和可行性。

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Cardiac supporting device using artificial rubber muscle: preliminary study to active dynamic cardiomyoplasty.使用人造橡胶肌肉的心脏支持装置:主动动态心肌成形术的初步研究
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本文引用的文献

1
Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children.柏林心脏公司 EXCOR 儿科心室辅助装置在美国儿童中用于心脏移植桥接。
Circulation. 2013 Apr 23;127(16):1702-11. doi: 10.1161/CIRCULATIONAHA.112.000685. Epub 2013 Mar 28.
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Pneumatic robotic systems for upper limb rehabilitation.用于上肢康复的气动机器人系统。
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RUPERT closed loop control design.鲁珀特闭环控制设计。
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:3686-9. doi: 10.1109/IEMBS.2010.5627647.
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Worldwide surgical experience with the Paracor HeartNet cardiac restraint device.全球使用Paracor HeartNet心脏约束装置的手术经验。
J Thorac Cardiovasc Surg. 2008 Jan;135(1):188-95. doi: 10.1016/j.jtcvs.2007.09.034.
5
Clinical evaluation of the CorCap Cardiac Support Device in patients with dilated cardiomyopathy.CorCap心脏支持装置在扩张型心肌病患者中的临床评估。
Ann Thorac Surg. 2007 Oct;84(4):1226-35. doi: 10.1016/j.athoracsur.2007.03.095.