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[因左支气管和同侧肺动脉狭窄机制导致呼吸衰竭的胸主动脉瘤——病例报告及文献复习]

[A thoracic aortic aneurysm with respiratory failure caused by the mechanisms of stenosis of the left bronchus and ipsilateral pulmonary artery--report of a case and review of the literature].

作者信息

Saitoh T, Wanibuchi Y, Terada Y, Shimoyama Y, Ino T, Furuta S

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1989 Dec;37(12):2553-7.

PMID:2625570
Abstract

Clinical symptoms of thoracic aortic aneurysm vary widely from symptoms resulting from its rupture to those due to compression of surrounding organs. Furthermore, the onset of symptoms is frequently followed by a fatal outcome unless emergency measures are taken. We have recently experienced a patient who developed respiratory insufficiency caused by an aneurysm of the descending thoracic aorta compressing the left primary bronchus and the right pulmonary artery, the former causing ventilatory failure in the left lung and the latter interfering with blood flow in the right lung. The patient underwent emergency prosthetic graft replacement and showed temporary symptom improvement. However, a postoperative complication of esophageal perforation due to ischemic necrosis occurred and eventually caused acute empyema followed by death. The patient was a 48-year-old male who presented with symptoms similar to bronchial asthma. Angiographic examination (iv-DSA) revealed compression of right pulmonary artery by an aneurysm of the descending thoracic aorta. Bronchoscopic findings included extramural stenosis of the left bronchus accompanied by arterial pulsation. As an emergency measure, artificial blood vessel replacement of the descending thoracic aorta was performed. However, the patient developed postoperative acute empyema and died on the 19th postoperative day. Autopsy revealed ischemic necrosis on the esophageal wall where the aneurysmal lesion had touched before operation. This seems to have formed a perforation into the left thoracic cavity and ultimately to have caused acute empyema. Since we believe that the pathogenesis and clinical course observed in this patient is rather rare, the case is reported in accompanied by relevant data from the literature.

摘要

胸主动脉瘤的临床症状差异很大,从破裂引起的症状到周围器官受压导致的症状都有。此外,除非采取紧急措施,症状出现后往往会导致致命后果。我们最近遇到一名患者,其降主动脉瘤压迫左主支气管和右肺动脉,导致呼吸功能不全,前者引起左肺通气衰竭,后者干扰右肺血流。患者接受了紧急人工血管置换术,症状暂时有所改善。然而,术后发生了缺血性坏死导致的食管穿孔并发症,最终引发急性脓胸,随后患者死亡。该患者为48岁男性,表现出类似支气管哮喘的症状。血管造影检查(静脉数字减影血管造影)显示降主动脉瘤压迫右肺动脉。支气管镜检查结果包括左支气管壁外狭窄并伴有动脉搏动。作为紧急措施,对降主动脉进行了人工血管置换。然而,患者术后发生急性脓胸,于术后第19天死亡。尸检发现术前动脉瘤病变接触部位的食管壁有缺血性坏死。这似乎形成了一个通向左侧胸腔的穿孔,最终导致急性脓胸。由于我们认为该患者观察到的发病机制和临床过程相当罕见,现报告该病例并附上相关文献资料。

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