Muneta T
Department of Orthopaedic Surgery, School of Medicine, Tokyo Medical and Dental University.
Nihon Seikeigeka Gakkai Zasshi. 1989 Dec;63(12):1502-12.
The effects of exercise on the biomechanical properties of the normal anterior cruciate ligament and bone specimen were investigated in two groups of rabbits: the one group with seven rabbits aged 7-8 months and the other with nine rabbits of 13-14 months. Four weeks of exercise produced significant increases in the maximum failure load, total absorbed energy to failure and stiffness in group of younger rabbits, but these changes were not seen in the older rabbits. Exercise effects on the remodelling of the reconstructed ACL were further studied in the two groups of rabbits, by observing macroscopic, histological, and biomechanical changes. While histologically normally structured ligament-bone junctions were seen partially in all the specimens, the specimen of the group with four weeks of exercise after 21 weeks after reconstructive surgery, showed a significant increase in stiffness of the reconstructed ACL. Macroscopically a glittering appearance was seen more frequently in the reconstructed ligament when compared to that of a cage-confined non-exercised group of rabbits.
一组有7只7 - 8个月大的兔子,另一组有9只13 - 14个月大的兔子。四周的运动使较年轻兔子组的最大破坏载荷、破坏时吸收的总能量和刚度显著增加,但在较年长的兔子中未观察到这些变化。通过观察宏观、组织学和生物力学变化,进一步研究了两组兔子运动对重建前交叉韧带重塑的影响。虽然在所有标本中部分可见组织学上结构正常的韧带 - 骨连接处,但在重建手术后21周进行四周运动的组的标本中,重建前交叉韧带的刚度显著增加。与笼养不运动的兔子组相比,重建韧带在宏观上更频繁地出现闪亮外观。