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[运用薄层色谱法对运动员血清白蛋白中脂质配体的研究]

[Study of lipid ligands in serum albumin in sportsmen using thin layer chromatography].

作者信息

Tolkacheva N V, Levachev M M, Kobozev G V, Safronova L G, Sorokina A G

出版信息

Kosm Biol Aviakosm Med. 1989 Nov-Dec;23(6):85-8.

PMID:2625985
Abstract

Lipid composition and the ability of serum albumin to bind lipid components and products of their peroxidation were investigated in cyclists of different rating during moderate workloads. Ratios of subfractions of phospholipids and other lipid metabolites in blood serum albumin were determined by the method of thin-layer chromatography. Diene conjugates and diene ketones were found to be actively formed in plasma of highly trained cyclists in whom a high lipid capacity of albumin was associated with its low affinity for lipid hydroperoxides.

摘要

在中等工作量下,对不同等级的自行车运动员的脂质组成以及血清白蛋白结合脂质成分及其过氧化产物的能力进行了研究。采用薄层色谱法测定血清白蛋白中磷脂亚组分与其他脂质代谢物的比例。结果发现,在高水平训练的自行车运动员血浆中,二烯共轭物和二烯酮大量生成,其中白蛋白的高脂质结合能力与其对脂质氢过氧化物的低亲和力相关。

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