Khanna Seema, Mishra Shashi Prakash, Kumar Satendra, Khanna Ajay Kumar
Department of General Surgery, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Department of General Surgery, RIMS, Safai, Uttar Pradesh, India.
BMJ Case Rep. 2015 Aug 10;2015:bcr2015210944. doi: 10.1136/bcr-2015-210944.
We present a rare case of carcinoma developing in an accessory breast. The patient presented with a progressive lump in her right axilla for 1 year. On examination, there was a well-developed nipple areola complex in the right axilla overlying a hard, fixed 5 × 3 cm lump. On investigation, core biopsy revealed poorly differentiated carcinoma of the breast. Mammography also revealed features of a malignant lesion with skin and muscle infiltration. Neoadjuvant chemotherapy was administered followed by modified radical mastectomy after three cycles. Immunohistochemistry study showed positive status of oestrogen and progesterone receptors, and negative HER-2 neu. Three more cycles of chemotherapy along with 50 Gy radiotherapy were given in an adjuvant setting followed by hormone therapy.
我们报告一例罕见的副乳发生癌变的病例。患者右腋窝出现进行性肿块1年。检查发现,右腋窝有发育良好的乳头乳晕复合体,其下方有一个坚硬、固定的5×3厘米肿块。经检查,粗针活检显示为乳腺低分化癌。乳腺钼靶检查也显示有恶性病变伴皮肤和肌肉浸润的特征。先进行了新辅助化疗,三个周期后行改良根治性乳房切除术。免疫组化研究显示雌激素和孕激素受体呈阳性,HER-2 neu呈阴性。在辅助治疗阶段又进行了三个周期的化疗以及50 Gy的放疗,随后进行了激素治疗。