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结节性肺淀粉样变性及原发性肺黏膜相关淋巴组织淋巴瘤伴广泛浆细胞分化所致明显骨化:1例罕见病例报告并文献复习

Nodular pulmonary amyloidosis and obvious ossification due to primary pulmonary MALT lymphoma with extensive plasmacytic differentiation: Report of a rare case and review of the literature.

作者信息

Xiang Hua, Wu Zuqun, Wang Zhaoming, Yao Hongtian

机构信息

Department of Pathology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou 310003, Zhejiang Province, China.

Department of Respiratory Medicine, The Second Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou 310009, Zhejiang Province, China.

出版信息

Int J Clin Exp Pathol. 2015 Jun 1;8(6):7482-7. eCollection 2015.

Abstract

Localized (primary) pulmonary amyloidosis associated with pulmonary low-grade B cell lymphoma is rarely occurred. Here we report an unusual case of nodular pulmonary amyloidosis and obvious ossification due to primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma with extensive plasmacytic differentiation in a 59-year-old man; moreover, two bronchial lymph nodes were involved histologically. The patient underwent a left lower lobectomy along with mediastinal lymphadenectomy. He received no adjuvant therapy and the postoperative course was uneventful within the 14 months follow-up period after his initial diagnosis.

摘要

与肺低度B细胞淋巴瘤相关的局限性(原发性)肺淀粉样变性很少发生。在此,我们报告一例罕见病例,一名59岁男性因原发性肺黏膜相关淋巴组织(MALT)淋巴瘤伴广泛浆细胞分化出现结节性肺淀粉样变性及明显骨化;此外,两个支气管淋巴结在组织学上也受累。该患者接受了左下肺叶切除术及纵隔淋巴结清扫术。他未接受辅助治疗,在初次诊断后的14个月随访期内术后过程平稳。

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