Marcassa C, Giordano A, Corrà U, Giannuzzi P
Cardiology Department, S. Maugeri Fnd, IRCCS, Scientific Institute of Veruno, Veruno, Italy.
Bioengineering Department, S. Maugeri Fnd, IRCCS, Scientific Institute of Veruno, Veruno, Italy.
Diabet Med. 2016 Aug;33(8):1067-75. doi: 10.1111/dme.12882. Epub 2015 Sep 6.
Diabetes increases the risk of in-hospital complications in medical or surgical patients. Few data are available in the rehabilitation phase after cardiac surgery.
To assess the influence of diabetes on outcome and complication rate in the rehabilitation phase after cardiac surgery.
Data prospectively recorded in the Hospital Information System from 5261 patients consecutively admitted between 1 January 2008 and 31 May 2013 for a comprehensive cardiac rehabilitation programme directly after cardiac surgery were analysed retrospectively.
The study cohort included 1285 (24%) patients with diabetes and 3976 (76%) without. Coronary artery bypass graft (CABG) was more frequent in patients with diabetes (58% vs. 37%, P < 0.01), and valvular surgery was more frequent in patients without diabetes (37% vs. 22%, P < 0.01). Patients with diabetes were more disabled after surgery, with severe disability (Barthel Index < 60) observed in 22% (vs. 17% in patients without diabetes, P < 0.001). During rehabilitation, complications were more frequent in patients with diabetes than those without (28% vs. 21%, P < 0.01); in particular, patients with diabetes had more infections, heart failure and more difficult surgical wound healing. However, the improvement in the Barthel Index was greater in patients with diabetes (+16 ± 15) than without (+13 ± 15, P < 0.001).
In a large cohort of patients directly admitted to an early inpatient rehabilitation programme after cardiac surgery, those with diabetes were more disabled. Nonetheless, and despite the higher rate of complications, patients with diabetes had the greatest benefit in terms of functional improvement.
糖尿病会增加内科或外科患者住院并发症的风险。心脏手术后康复阶段的相关数据较少。
评估糖尿病对心脏手术后康复阶段结局和并发症发生率的影响。
回顾性分析2008年1月1日至2013年5月31日期间连续收治的5261例患者的医院信息系统前瞻性记录数据,这些患者均在心脏手术后直接接受全面心脏康复计划。
研究队列包括1285例(24%)糖尿病患者和3976例(76%)非糖尿病患者。糖尿病患者冠状动脉旁路移植术(CABG)更为常见(58%对37%,P<0.01),非糖尿病患者瓣膜手术更为常见(37%对22%,P<0.01)。糖尿病患者术后残疾程度更高,22%的患者出现严重残疾(Barthel指数<60)(非糖尿病患者为17%,P<0.001)。在康复期间,糖尿病患者的并发症比非糖尿病患者更常见(28%对21%,P<0.01);特别是,糖尿病患者有更多感染、心力衰竭,手术伤口愈合更困难。然而,糖尿病患者的Barthel指数改善幅度更大(+16±15),高于非糖尿病患者(+13±15,P<0.001)。
在一大群心脏手术后直接进入早期住院康复计划的患者中,糖尿病患者残疾程度更高。尽管如此,尽管并发症发生率较高,但糖尿病患者在功能改善方面获益最大。