Wijerathne Buddhika T B, Meier Robert J, Agampodi Thilini C, Agampodi Suneth B
Department of Forensic Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka.
Department of Anthropology, Indiana University, Bloomington, IN, USA.
J Physiol Anthropol. 2015 Aug 12;34(1):29. doi: 10.1186/s40101-015-0065-3.
Hypertension is a major contributor to the global burden of disease and mortality. A major medical advancement would be a better means to ascertain which persons are at higher risk for becoming hypertensive beforehand. To that end, there have been a number of studies showing that certain dermatoglyphic markers are associated with hypertension. This association could be explained if the risk toward developing hypertension later on in life is somehow connected with fetal development of dermatoglyphics. It would be highly valuable from a clinical standpoint if this conjecture could be substantiated since dermatoglyphic markers could then be used for screening out individuals who might be at an elevated risk of becoming hypertensive. The aim of this review was to search for and appraise available studies that pertain to the association between hypertension and dermatoglyphics.A systematic literature search conducted using articles from MEDLINE (PubMed), Trip, Cochran, Google scholar, and gray literature until December 2014. Of the 37 relevant publications, 17 were included in the review. The review performed according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement.This review showed a fairly consistent finding of an increased frequency of whorl patterns along with a higher mean total ridge count in digital dermatoglyphic results in hypertensive samples compared to controls. However, it was imperative to discuss several limitations found in the studies that could make this association as yet unsettled.
高血压是全球疾病负担和死亡率的主要促成因素。一项重大的医学进展将是找到一种更好的方法,以便预先确定哪些人患高血压的风险更高。为此,已有多项研究表明某些皮纹标记与高血压有关。如果日后患高血压的风险与皮纹的胎儿发育以某种方式相关,那么这种关联就可以得到解释。从临床角度来看,如果这一推测能够得到证实,那将具有很高的价值,因为皮纹标记随后可用于筛查出可能患高血压风险较高的个体。本综述的目的是检索和评估与高血压和皮纹之间关联相关的现有研究。使用来自MEDLINE(PubMed)、Trip、Cochran、谷歌学术和灰色文献的文章进行了系统的文献检索,直至2014年12月。在37篇相关出版物中,17篇被纳入本综述。本综述按照系统评价和荟萃分析的首选报告项目(PRISMA)声明进行。本综述显示了一个相当一致的发现,即与对照组相比,高血压样本的手部皮纹结果中涡纹模式的频率增加,同时平均总嵴数更高。然而,有必要讨论这些研究中发现的几个局限性,这些局限性可能使这种关联尚未确定。