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与精神分裂症及其临床亚型相关的皮纹学主要特征。

Main characteristics of dermatoglypics associated with schizophrenia and its clinical subtypes.

机构信息

National Center of Mental Health, Ministry of Health, Ulaanbaatar, Mongolia.

Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.

出版信息

PLoS One. 2021 Jun 10;16(6):e0252831. doi: 10.1371/journal.pone.0252831. eCollection 2021.

Abstract

Dermatoglypic patterns are extensively investigated to apply in disease-related risk assessment due to an obvious association between morphological and genetic characteristics. In the current study, we aimed to determine whether the fingerprint and palmar patterns vary between case population with schizophrenia and general population. A cross sectional study was conducted in people diagnosed with schizophrenia (cases) and a control population between 2016 and 2019. In this study, 252 people were participated. Ink and paper method was used to evaluate the difference of fingerprints palm prints between patients with schizophrenia and participants in control group.93 participants were analyzed in schizophrenic group and 142 participants were investigated in the control group. The percentage of arches on the right ring finger was significantly different between the schizophrenic patient group and control group (p = 0.011). The whorl pattern type (U-W-U-W-W-W-W-U-W-U) was dominantly observed in both of the schizophrenic patient group and control group. A-B ridge count in schizophrenic patient group and control group produced a markedly significant difference (p<0.05). Interestingly, a strong significant difference was produced in comparing of A-B ridge count in catatonic schizophrenia group with residual schizophrenia group (p<0.005). In comparison, index of pattern intensity in control group was slightly higher than that in schizophrenic patient group. Taking together, these results showed that the dermatoglypic characteristics might be a valuable tool to describe the nature of schizophrenia and its clinical subtypes and further studies are needed in clinical application.

摘要

指纹图谱广泛应用于疾病相关风险评估,因为形态和遗传特征之间存在明显的关联。在本研究中,我们旨在确定精神分裂症患者人群和普通人群之间指纹和掌纹模式是否存在差异。2016 年至 2019 年期间,我们进行了一项横断面研究,纳入了被诊断为精神分裂症的患者(病例组)和对照组人群。本研究共纳入 252 人。使用墨水和纸张的方法评估了精神分裂症患者和对照组参与者之间指纹和掌纹的差异。在精神分裂症组中分析了 93 名参与者,在对照组中调查了 142 名参与者。右环指的弓形纹百分比在精神分裂症患者组和对照组之间存在显著差异(p = 0.011)。精神分裂症患者组和对照组中均主要观察到 U-W-U-W-W-W-W-U-W-U 型斗纹。精神分裂症患者组和对照组的 A-B 嵴线计数存在显著差异(p<0.05)。有趣的是,紧张型精神分裂症组与残留型精神分裂症组的 A-B 嵴线计数比较产生了强烈的显著差异(p<0.005)。相比之下,对照组的模式强度指数略高于精神分裂症患者组。综上所述,这些结果表明,皮肤纹理学特征可能是描述精神分裂症及其临床亚型本质的一种有价值的工具,需要进一步在临床应用中进行研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8b1/8191880/87650312a9c3/pone.0252831.g001.jpg

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