伪装成吉兰-巴雷综合征的急性髓系白血病复发：简要报告及文献复习
Pseudo-Guillain-Barré syndrome masking acute myeloid leukemia relapse: Brief report and review.
作者信息
El Karak Fadi, El Rassy Elie, Tabchi Samer, Chouery Eliane, Megarbane Andre, Kattan Joseph
机构信息
Hematology-Oncology Department, Hotel Dieu de France Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Unité de Génétique Médicale et Laboratoire Associé INSERM à l'unité UMR_S 910, Pôle Technologie Santé, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
出版信息
Leuk Res Rep. 2015 Jul 17;4(2):42-4. doi: 10.1016/j.lrr.2015.05.002. eCollection 2015.
Central nervous system (CNS) relapse is not a rare presentation in acute myeloid leukemia (AML) as its incidence ranges between 2% and 9%. It manifests with meningeal leukemia, cranial nerve palsies or cerebral mesenchymal myeloid sarcoma. We herein report the case of a 69 year-old female that presented a pseudo-Guillain-Barré syndrome masking an AML CNS relapse. Her symptoms completely resolved upon administration of a tailored treatment. This case suggests that puzzling neurological manifestations in patients with a history of AML should be considered as a CNS recurrence and investigated accordingly even in the context of normal imaging findings.
中枢神经系统（CNS）复发在急性髓系白血病（AML）中并非罕见表现，其发生率在2%至9%之间。它表现为脑膜白血病、颅神经麻痹或脑间质性髓样肉瘤。我们在此报告一例69岁女性病例，该患者表现为伪装成吉兰-巴雷综合征的AML中枢神经系统复发。给予针对性治疗后，她的症状完全缓解。该病例表明，有AML病史的患者出现令人困惑的神经表现时，即使影像学检查结果正常，也应考虑为中枢神经系统复发并进行相应检查。
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