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成人严重间日疟原虫非脑型疟疾中的视网膜出血

Retinal Hemorrhages in Severe Non-cerebral Plasmodium vivax Malaria in an Adult.

作者信息

Lakhotia Manoj, Singh Jagdish, Pahadiya Hans Raj, Kumar Harish, Choudhary Prakash K

机构信息

Senior Professor, Department of Medicine, Dr. SNMC Jodhpur, Rajasthan, India .

Senior Resident, Department of Medicine, Dr. SNMC Jodhpur, Rajasthan, India .

出版信息

J Clin Diagn Res. 2015 Jun;9(6):OD01-3. doi: 10.7860/JCDR/2015/11930.6003. Epub 2015 Jun 1.

Abstract

Malaria is the most important parasitic diseases of humans and one of the leading causes of morbidity and mortality in tropical countries. Earlier Plasmodium vivax was considered as a benign infection, but now it is recognized as a cause of severe malarial disease. It causes severe malarial disease similar to those as Plasmodium falciparum including cerebral malaria, severe anaemia, severe thrombocytopenia, hepatic dysfunction, shock, acute respiratory distress syndrome (ARDS), acute renal failure, and pulmonary oedema. Malarial retinopathy includes retinal whitening, vessel changes, retinal hemorrhages and papilledema. However, retinal hemorrhages are very rare in Plasmodium vivax infestation. Hereby, we report a case of 30-year-old man, who presented with fever with chills and diminution of vision. He was found to have Plasmodium vivax infection with retinal hemorrhages. He was treated successfully with artisunate, primaquine and doxycycline, completely recovered after one month.

摘要

疟疾是人类最重要的寄生虫病,也是热带国家发病和死亡的主要原因之一。早期间日疟原虫被认为是一种良性感染,但现在它被认为是严重疟疾疾病的病因。它会引发与恶性疟原虫类似的严重疟疾疾病,包括脑型疟疾、严重贫血、严重血小板减少、肝功能障碍、休克、急性呼吸窘迫综合征(ARDS)、急性肾衰竭和肺水肿。疟疾视网膜病变包括视网膜变白、血管改变、视网膜出血和视乳头水肿。然而,间日疟原虫感染中视网膜出血非常罕见。在此,我们报告一例30岁男性病例,该患者出现发热伴寒战及视力减退。他被发现感染间日疟原虫且伴有视网膜出血。他接受了青蒿琥酯、伯氨喹和多西环素治疗,一个月后完全康复。

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