Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Am J Trop Med Hyg. 2010 Feb;82(2):219-22. doi: 10.4269/ajtmh.2010.09-0439.
Retinal hemorrhage is a frequently observed sign in Plasmodium falciparum infection. In Plasmodium vivax infection, however, retinal hemorrhage is very rare; only five cases have been reported in the literature. In this case report, we review the literature and the case of 52-year-old man who had retinal hemorrhages in P. vivax infection. We analyzed the structural characteristics of the lesions using fluorescein angiography and spectral-domain optical coherence tomography. Physicians should be aware of the possibility of retinal hemorrhage in malaria patients, even those with P. vivax infection, and should consider a diagnosis of malaria in a patient with unexplained retinal hemorrhage and fever.
视网膜出血是恶性疟原虫感染中常见的征象。然而，在间日疟原虫感染中，视网膜出血非常罕见；文献中仅报道了 5 例。在本病例报告中，我们复习了文献并报告了 1 例 52 岁男性因间日疟原虫感染而发生视网膜出血的病例。我们通过荧光素血管造影和频域光相干断层扫描分析了病变的结构特征。医生应意识到疟疾患者（甚至是间日疟原虫感染者）发生视网膜出血的可能性，如果出现不明原因的视网膜出血和发热，应考虑疟疾的诊断。
