Hu S J, Zhu J
Sheng Li Xue Bao. 1989 Dec;41(6):592-6.
Injection of a compound algogenic substance into receptive field of the skin induced sustained discharges of polymodal nociceptors in rats. The sustained discharges were obviously increased by stimulation of the sympathetic nerve innervating the receptive field. Initial facilitation was followed by the inhibition of discharges in partial units. The sympathetic effect can be activated repeatedly and lasted for a prolonged time. Injection of norepinephrine (5 micrograms/0.2 ml) into the local artery could cause the similar effect. Results indicate that the sympathetic efferents facilitates the sustained discharges of polymodal nociceptors. The possibility of producing causalgia and contrary results of experiments were discussed.
向大鼠皮肤的感受野内注射复合致痛物质可诱发多模式伤害感受器的持续放电。支配该感受野的交感神经受到刺激后，持续放电明显增加。部分单位在最初的易化之后放电受到抑制。交感效应可反复激活并持续较长时间。向局部动脉注射去甲肾上腺素（5微克/0.2毫升）可产生类似效应。结果表明，交感传出神经促进多模式伤害感受器的持续放电。文中讨论了产生灼性神经痛的可能性及实验的相反结果。
