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穿透伤后早期复苏模式与死亡率的关系。

Patterns of early resuscitation associated with mortality after penetrating injuries.

机构信息

Department of Trauma and Orthopaedic Surgery, University of Witten/Herdecke, Cologne-Merheim Medical Centre, Cologne, Germany.

IFOM - Institute for Research in Operative Medicine, University of Witten/Herdecke, Cologne, Germany.

出版信息

Br J Surg. 2015 Sep;102(10):1220-8; discussion 1228. doi: 10.1002/bjs.9869.

Abstract

BACKGROUND

Penetrating injuries are rare in European populations so their management represents a particular challenge. The aim was to assess early therapeutic aspects that are associated with favourable outcomes in patients with penetrating trauma.

METHODS

Patients with penetrating injuries documented from 2009 to 2013 in the TraumaRegister DGU® were analysed. Patients with a primary admission and an Injury Severity Score (ISS) of at least 9 were included. The Revised Injury Severity Classification (RISC) II score was used for mortality prediction, and a standardized mortality ratio (SMR) calculated per hospital. Hospitals with favourable outcome (SMR below 1) were compared with those with poor outcome (SMR 1 or more).

RESULTS

A total of 50 centres had favourable outcome (1242 patients; observed mortality rate 15.7 per cent) and 34 centres had poor outcome (918 patients; observed mortality rate 24.4 per cent). Predicted mortality rates according to RISC-II were 20.4 and 20.5 per cent respectively. Mean(s.d.) ISS values were 22(14) versus 21(14) (P = 0.121). Patients in the favourable outcome group had a significantly shorter time before admission to hospital and a lower intubation rate. They received smaller quantities of intravenous fluids on admission to the emergency room, but larger amounts of fresh frozen plasma, and were more likely to receive haemostatic agents. A higher proportion of patients in the favourable outcome group were treated in a level I trauma centre. Independent risk factors for hospital death following penetrating trauma identified by multivariable analysis included gunshot injury mechanism and treatment in non-level I centres.

CONCLUSION

Among penetrating traumas, gunshot injuries pose an independent risk of death. Treatment of penetrating trauma in a level I trauma centre was significantly and independently associated with lower hospital mortality.

摘要

背景

穿透性损伤在欧洲人群中较为罕见,因此其治疗极具挑战性。本研究旨在评估与穿透性创伤患者良好预后相关的早期治疗方面。

方法

分析了 2009 年至 2013 年创伤登记处 DGU®中记录的穿透性损伤患者。纳入了有原发性住院和损伤严重程度评分(ISS)至少 9 分的患者。采用修订损伤严重程度分类(RISC)Ⅱ评分进行死亡率预测,并按医院计算标准化死亡率比(SMR)。将预后良好(SMR<1)的医院与预后不良(SMR≥1)的医院进行比较。

结果

共有 50 家医院预后良好(1242 例患者;观察死亡率为 15.7%),34 家医院预后不良(918 例患者;观察死亡率为 24.4%)。根据 RISC-II 预测的死亡率分别为 20.4%和 20.5%。平均(标准差)ISS 值分别为 22(14)与 21(14)(P=0.121)。预后良好组患者从受伤到入院的时间明显缩短,气管插管率较低。他们在急诊室入院时接受的静脉输液量较小,但接受的新鲜冷冻血浆量较大,更有可能接受止血剂。预后良好组患者中有更高比例的患者在一级创伤中心接受治疗。多变量分析确定的穿透性创伤后医院死亡的独立危险因素包括枪伤机制和在非一级中心治疗。

结论

在穿透性创伤中,枪伤独立增加死亡风险。在一级创伤中心治疗穿透性创伤与医院死亡率降低显著相关。

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